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Aluminum chloride impaired spatial memory, but not senile plaques formation in the rat model of Alzheimer’s disease Narwanto, Muhammad Ihwan; Rahayu, Masruroh; Soeharto, Setyawati; Nurdiana, Nurdiana
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 13, No 1 (2022): June 2022
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (366.4 KB) | DOI: 10.30659/sainsmed.v13i1.18102

Abstract

Aluminum compounds can be easily found in the environment. Aluminum contamination is the environmental factor as one of the risk factors for Alzheimer's disease (AD). In the animal model, aluminum chloride (AlCl3) induces inflammation and oxidative stress. Inflammation and oxidative stress are important pathogenesis pathways in the AD. This study was conducted to determine whether AlCl3 can impair spatial memory and induce senile plaques formation. A total of 24 young adult Wistar rats were used in this study. The rats were divided into four groups; one control group and three AlCl3 treated groups with doses of 150 mg/kg, 300 mg/kg, and 600 mg/kg, respectively for 8 weeks. The spatial memory test was measured using Morris water maze and the histopathology was done by identification of senile plaques formation in the hippocampal tissue. Statistical analysis was performed using one-way analysis of variance (ANOVA) followed by Tukey's test for multiple comparisons. The level of statistical significance was set at a p value < 0.05. This study showed that there are significant differences (p<0,05) between the control group and all the AlCl3 treatment groups in the memory test, however, there is no change in the senile plaque’s expression in all groups. Administration of AlCl3 for 8 weeks can cause the impaired of spatial memory without senile plaques formation.
The Implementation of Independent Curriculum at State Vocational High School Nasution, Rizki Hasanah; Wirtati, Ira; Nurojiyah, Siti; Nurdiana, Nurdiana; Mesiono, Mesiono
EDUTEC : Journal of Education And Technology Vol 7 No 3 (2024): March 2024
Publisher : STAI Miftahul Ula Nganjuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29062/edu.v7i3.814

Abstract

This article discusses the evolution of the education curriculum in Indonesia from 1947 to the present day, undergoing changes eleven times to align with the goals outlined in Law Number 20 of 2003. The shift from the 2013 curriculum to the independent curriculum was prompted by challenges such as low literacy and numeracy skills of students, highlighted by the Program for International Student Assessment (PISA) study in 2018. The Covid-19 pandemic further emphasized the need for curriculum changes to recover from learning loss. The independent curriculum provides schools, especially students, the freedom to choose based on their needs, focusing on freedom and creative thinking. The study employs a qualitative research approach with a case study design, conducted from October 2023 to December 2023. The object is the implementation of the independent curriculum at SMK Negeri 2 Tebing Tinggi, and the subjects include two lead teachers and one curriculum teacher. Data collection involves interviews, direct observation, and documentation of relevant materials. The independent curriculum at SMK Negeri 2 Tebing Tinggi focuses on fostering independent and self-reliant students. The implementation involves various stages, including participation in training activities, workshops, and self-training through the Merdeka Mengajar Platform. Challenges include changing regulations, low teacher experience, and limited facilities. Challenges in the implementation include changing regulations, low teacher experience, limited references, digital access limitations, and inadequate facilities. Despite challenges, SMK Negeri 2 Tebing Tinggi has been successful in implementing the independent curriculum, focusing on intracurricular, curricular, and extracurricular learning principles.
Study on Educational Management and Development of Educational Institutions Wirtati, Ira; Nurdiana, Nurdiana
EDUTEC : Journal of Education And Technology Vol 8 No 1 (2024): September 2024
Publisher : STAI Miftahul Ula Nganjuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29062/edu.v8i1.927

Abstract

This study aims to examine the development model of Islamic educational institutions, specifically focusing on MTs Islamiyah YPI Batang Kuis, to understand the stages and strategies utilized in managing institutional growth and curriculum integration. Using a qualitative, phenomenological approach, this research collects data through observation, interviews, and documentation. Findings reveal a four-stage institutional development model: (1) Diagnosis, where the madrasah head identifies and analyzes institutional challenges; (2) Intervention, which involves implementing solutions to address these challenges; (3) Evaluation, through which the outcomes of interventions are assessed; and (4) Maintenance, aiming to sustain and refine the positive results achieved. Furthermore, MTs Islamiyah YPI Batang Kuis operates as a full-day school, utilizing a dual-curriculum model from both the Ministry of National Education and the Ministry of Religious Affairs, highlighting a structured approach to Islamic education management.
Proses Pembuatan Mesin Pengiris Buah Pinang Model Pisau Rotari Kapasitas 25 Kg/Jam Irfansyah, M.; Lubis, Zulkifli; Oppusunggu, Kamrul; Nurdiana, Nurdiana
IRA Jurnal Teknik Mesin dan Aplikasinya (IRAJTMA) Vol 1 No 2 (2022): Agustus
Publisher : CV. IRA PUBLISHING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56862/irajtma.v1i2.12

Abstract

Areca fruit slicing machine, with a capacity of 25 kg/hour, has a machine construction consisting of a drive mechanism, an inlet mechanism, an outlet mechanism and a slicing mechanism. The areca fruit slicing mechanism uses the main components such as the pressure handle, inlet, disc carrying the blade, and the slicing knife. At the same time, the drive mechanism uses supporting components such as intermediate shafts, reducers, gears, pulleys and belts. The manufacture of this machine uses machine tools, including lathes, grinding machines, cutting grinding machines, drill/drilling machines, milling machines and welding machines. At the same time, the components made include the machine frame, drive shaft, pressure handle, slicing blade, disc carrying blade, inlet, outlet, and casing cover. Time calculation can be done by planning the work steps of the manufacturing process for each component, including the procurement of materials, measurements, processes, time intervals (wasted time) and finishing. From the work results, it was obtained that the total time for making eight components and assembling was 1094.48 minutes (18.24 hours).
Manufaktur dan Pengujian Burner LPG untuk Pemanasan Heater Mesin Stirling mCHPSE-012021 Hidayat, Muhammad Arif; Al Ridho, Fatur Fadhillah; Jufrizal, Jufrizal; Supriatno, Supriatno; Nurdiana, Nurdiana
IRA Jurnal Teknik Mesin dan Aplikasinya (IRAJTMA) Vol 2 No 3 (2023): Desember
Publisher : CV. IRA PUBLISHING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56862/irajtma.v2i3.82

Abstract

This research focuses on developing a special LPG burner for the mCHPSE-012021 Stirling engine. The burner design was developed using CAD software and fabricated using machine tools and a welding process. Tests are carried out to verify how much the burner performance meets the desired specifications. The test results show that although the burner can reach the required high temperature, the thermal efficiency is still low, at 19.72%. This figure is far below the efficiency standard for household gas stoves, according to SNI 8660:2018. These findings highlight the urgency of improving burner design and efficiency to meet established standards, improving the mCHPSE-012021 Stirling engine's overall performance, and significantly increasing energy efficiency. These improvements are necessary to ensure optimal performance and efficiency in energy use in mCHPSE systems, underscoring the importance of developing more efficient and standards-compliant burner technology to support the use of Stirling engines in microenergy applications.
Analisis Efisiensi Thermal dan Konsumsi Bahan Bakar pada Burner Kompor SNI Sebagai Dasar Acuan Perencanaan Burner Mesin Stirling Lubis, Rahmadsyah; Jufrizal, Jufrizal; Supriatno, Supriatno; Nurdiana, Nurdiana
IRA Jurnal Teknik Mesin dan Aplikasinya (IRAJTMA) Vol 3 No 2 (2024): Agustus
Publisher : CV. IRA PUBLISHING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56862/irajtma.v3i2.96

Abstract

This study aims to evaluate the performance of an LPG stove burner by assessing the flame temperature, fuel consumption, burner power, and thermal efficiency. The method employed is an experimental approach using a water boiling technique. The test materials used include 3 kg of LPG gas and water. The equipment utilized includes an SNI-compliant cooking stove, a pot, a digital scale, a rotameter flow meter, a gas regulator and hose, a stopwatch, a UT320D thermometer controller, an NPT stainless steel thermometer, and thermocouple sensor cables. The results show that during the first test with the stove set to the minimum setting, the average flame temperature at the burner reached 559.005 °C, with a maximum value of 589.2 °C. In the second test, with the stove set to the maximum setting, the average flame temperature reached 714.78 °C, with a maximum value of 769.3 °C. Fuel consumption was recorded at 0.391 kg in the first test and 0.545 kg in the second test. The burner power output was 1.754 kW in the first test and 2.225 kW in the second test. The thermal efficiency of the burner was recorded at 50.07% in the first test, increasing to 52.85% in the second test. The measurement and analysis of thermal efficiency and fuel consumption in this study can serve as a crucial guide in designing and developing burners for Stirling engines.
Pengembangan Pembelajaran Kecakapan Hidup Berbasis Karakter Kewirausahaan pada Jenjang Sekolah Dasar Hasan, Muhammad; Azizah, Nurul; Nurjannah, Nurjannah; Nurdiana, Nurdiana; Arisah, Nur
Jurnal Basicedu Vol. 6 No. 3 (2022)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/basicedu.v6i3.2791

Abstract

Penelitian ini bertujuan untuk mengetahui pengembangan pembelajaran kecakapan hidup berbasis karakter kewirausahaan pada jenjang pendidikan dasar. Penelitian ini dilakukan dengan menggunakan pendekatan kualitatif dengan menggunakan sistem coding. Teknik pengumpulan data dalam kajian ini dilakukan melalui observasi dan juga wawancara. Informan dalam penelitian ini adalah kepala sekolah dan guru di SDN 90 Mattumpu. Analisis data dengan sistem coding dilakukan dalam 2 tahap, yaitu initial coding dan focused coding. Hasil kajian ini menemukan bahwa guru di SDN 90 Mattumpu sudah mengetahui dan memahami pendidikan karakter kewirausahaan dan nilai-nilai kewirausahaan tetapi belum menerapkan secara maksimal. Temuan lain menunjukkan bahwa kepala sekolah dan guru SDN 90 Mattumpu mengakui bahwa nilai-nilai karakter kewirausahaan sangat penting untuk diterapkan kepada siswa-siswa agar mempunyai bekal dasar agar mereka mulai diperkenalkan dan tertarik dengan kegiatan berwirausaha. Pengembangan pembelajaran dalam persepktif pendidikan kewirausahaan pada jenjang pendidikan dasar diarahkan untuk pengembagan berbagai keterampilan akademik dan keterampilan sosial (soft skill) yang terinternalisasi dalam kecakapan hidup general.
Utilization Edugames Baamboozle as an Evaluation Media for the Biology Cognitive Abilities of Class 14 Bone High School Students Nurdiana, Nurdiana; Wahyuni, Sri; Asmah, Sitti
Jurnal Pendidikan Biologi Vol 13, No 2 (2024): Jurnal Pendidikan Biologi
Publisher : Magister Pendidikan Biologi, Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpb.v13i2.61880

Abstract

This research aims to find out how the Edugames baamboozle media is used as an evaluation medium for the biology cognitive abilities of class X students at SMAN 14 Bone. The research used is quantitative research with the Pre-Experimental Design type of research with the One Group Pre-test and Post-test Design type. The data collection technique used in this research is giving a pre-test and post-test in the form of multiple choice and documentation. The results of inferential analysis using three tests, namely normality test, homogeneity test and hypothesis test, are known from the results of normality data analysis using one Kolmogrov-Smirnov test, pre-test 0.83 ˃ 0.05 and post-test 0.37 > 0.05 (normal ). The homogeneity test using Levene Statistics shows 0.32 ˃ 0.05 (homogeneous) and based on the t test using the Paired-test the significant rate used is α = 0.05. The data obtained is significant (0.000) ˂ = 0.05, thus H0 is rejected and there was acceptance of H1 which showed that there was effectiveness before the treatment was given and after the treatment using the Edugames baamboozle media. Based on research conducted at SMAN 14 Bone, the average pre-test score was 39.7, while the average post-test score was 85.0. The post-test score was higher than the pre-test score. It can be concluded that through the Edugames baamboozle media it has an influence on the Biology cognitive abilities of class XI students at SMAN 14 Bone and they provide a positive response to this learning media.
Determinan Keteraturan Kunjungan Masa Nifas di Puskesmas Topore Kabupaten Mamuju Ashari, Agus Erwin; Nurdiana, Nurdiana
Jurnal Kebidanan Malakbi Vol 1 No 2 (2020): Agustus 2020
Publisher : Jurusan Kebidanan Poltekkes Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/b.v1i2.305

Abstract

The Maternal Mortality Rate in Indonesia according to SUPAS in 2015 is 305 per 100,000 live births. The number of maternal deaths in Mamuju District in 2015 was 12 people or 218 per 100,000 live births. The coverage of postpartum visits (KF3) in West Sulawesi Province tended to decline from 2012 to 2017. Post-natal visits in Mamuju District were 78.02% and in 2016 84.5%. The research objective was to determine the determinants that affect the regularity of postpartum visits. This study used a descriptive analytic design with a cross sectional approach. The sample in this study were postpartum mothers whose postpartum period had been completed and had a KIA book in the work area of ​​Puskesmas Topore from March to October 2018, namely 45 postpartum mothers who were selected by simple random sampling. The results showed that statistically there was no relationship between education and regular postpartum visits (p = 0.613). There was no relationship between work and regularity of postpartum visits (p = 0.063), there was no relationship between parity and regularity of postpartum visits (p = 0.481).
Waktu Mulai, Durasi IMD dan Keberhasilan ASI Eksklusif idayati, Idayati; Amin, Erna; sastrariah, Sastrariah; Wahida, Wahida; Nurdiana, Nurdiana; Cicilia, Fitri
Jurnal Kebidanan Malakbi Vol 5 No 1 (2024): Januari 2024
Publisher : Jurusan Kebidanan Poltekkes Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/b.v5i1.1228

Abstract

Early initiation of breastfeeding (EIBF) is crucial for exclusive breastfeeding success and has many benefits for mothers, babies, and families. Moreover, EIBF also contributes to building the quality of the next generation. This study aims to investigate the factors that determine the implementation of EIBF and its effect on exclusive breastfeeding during the postpartum period. The research used an observational analytic approach with a prospective cohort design on all mothers who gave birth in health facilities in the Beru-beru Health Center working area, West Sulawesi Province in 2021. The research sample included mothers who gave birth in the same area, and were willing to participate as respondents and living in the location. The results of the Chi-Square test analysis showed that the start time and duration of EIBF implementation affected exclusive postpartum breastfeeding, with respective p-values of less than 0.001 and 0.001. This research highlights the importance of implementing EIBF by initiating immediate breastfeeding within five minutes after the baby is born and continuing it for at least one hour. Both the start time and duration of EIBF complement each other in achieving successful postpartum exclusive breastfeeding.
Co-Authors - Afrizal A F, IKKA KARTIKA A.A. Ketut Agung Cahyawan W Abbas Mahmud Abd. Rasyid Syamsuri Abdul Muis Afdal, Moh Afrianti, Rima Afrizal, John Agus Erwin Ashari Agus Rianto Agustina Tri Endharti Ahmad Fauzan Ainun Nizar Masbuchin, Ainun Nizar Aisa, Nur Akhmalia, Qorry' Afyu Al Ridho, Fatur Fadhillah Al-Kadafi, Muammar Alfiyaty, Rizky Alimina, Naslina Amalia Nabila, Nila Amin, Amelia Rezki Septiani Amin, Erna Ananta, Azra Andina Devi Arvita, Andina Devi Angka, Andi Werawe Annisa Annisa Annisa' Wigati Rozifa Anshar, Ashari ANWAR, ALZANI SAEFUL Ardi Andika, Ardi Ardi Eko Mulyawan Arfah, Mahrani Arfiani, Irfa Ariani, Rini Arifin, Fakhira Asfira, Rizka Asih, Aliyah Tresna Asmah, Sitti Asmi Asmi Astari, Pocut Astriani, Riza Astuti, Crisyanti Windi Astuti, Yayuk Dwi Aulia Chaya Kusuma, Aulia Chaya Aunurrahman Aunurrahman Azahra, Mutiara Syifa Bagus Putu Suryana, Bagus Putu Bambang Rahardjo Bambang Setiawan Baso, Aris Br Bangun, Eva Riana Candra, Ifan Aulia Cangara, Arie Syahruni Christianto, Antonius Chusyairi, Onnitia Dwi Putri Cicilia, Fitri Damanik, Emeliya Sukma Dara Dantara, Tri W.I. Dendodi, Dendodi Dermawan, Rezki Desfryda, Elynca Putri Destri Wahyuningsih desy wulandari Dewi Chrisna Wulandari, Dewi Chrisna Dewi Purnama Sari Dewi, Elvira S. Dhea P, Errita Dian Hasanah Dianita, Oktia Risa Didiek Darmadi Ts Dinar, Muhammad Dinastiti, Vide Bahtera Dwi Sarbini Dwinadella, Sephia Elpisah Elvira Sari Dewi Erawati, Dini Rachma Erliera . Erna Amin Erny Erny, Erny erwanto, Agus esso, andi sawe ri Eviana Norahmawati evyanto, winda Fachrurrozi Fachrurrozi FADIAH, NUR Fadillah, Fitri Emi Fahruddin Fahruddin Fajar Ari Nugroho fatchiyah . Fatmawati Fatmawati Fitri, Aidi Fitriani Puspa Ningsih Gadis Mutiara PI, Gadis Mutiara Ginting, Regunanta Gosari, Benny Audy Jaya Gusmuliana, Paidi Gusti, Kharisma Ciptaning Hanapi, Hanapi Handono Kalim Hani Susianti Hanny Handiyani Harry Yulianto, Harry Hasanah, Dillah Faradillah Hasibuan, Akbar Farid Hastuti, Nur Aini Retno Heriansah, Heriansah Hermiyanty Hermiyanty, Hermiyanty Hikmah, Mamluatul HMS Chandra Kusuma Idayati Idayati, Idayati Ihda Dian Kusuma Iin Suryaningsih Imansari, Adillah Imelda Avia immawanti, immawanti Inanna, Inanna Indah Damayanti, Indah Indahsari, Yustika Ingtias, Fatma Tresno Irawan, Dwi Dianita Irfansyah, M. isnain, Fahmi Izaak Zoelkarnain Akbar, Izaak Zoelkarnain Izza, Syarifatul JA, Adewiyah Jamaluddin Jamaluddin Jamaluddin Nasution Janasti, Laksmitha Jeanette T. Momongan Jufrizal Jufrizal Jufrizal Jufrizal Juliansari, Rike Kamaruddin, Citra Ayni Kariani, Ni Ketut Kasim, Ma'ruf Kenty Wantri Anita, Kenty Wantri Khoirurrosyidin, Khoirurrosyidin Krisna Yetti KUDADIRI, RAPSANJANI Kuna, Sri Fadlia Kuntarti Kurniawan, Aldi Kurniawan, Eprian Kusworini Handono La Baco S Laksmi Karunia Tanuwijaya Lestari, Tiara Lidwina Faraline Triprisila Loeki Enggar Fitri Lubis, Rahmadsyah M. Aris Widodo M. Ihwan Narwanto Maman Rachman Manggabarani, Andi Maghfira Marina Marina Marsa, Abdurrahman Hadi, Marsha, Marsha Maryata, Maryata Masfufah Masfufah, Masfufah Mashuri Mashuri Masiyati, Eti Masruroh Rahayu, Masruroh Mawaddah, Shohipatul Mesiono, Mesiono Metalita, Eva Mindiani, Mindiani Muhammad Anshory, Muhammad Muhammad Arif Hidayat Muhammad Hasan Muhammad Hasan Muhammad Ihsan Said Ahmad Muhammad Imam Ma'ruf Muhammad Noor Muhammad Nur Mulyono, Didik Munir, Wahida Museliza, Virna Muspa, Muspa Mustari Mustari Nanda, Britania Laila Nas, Wadzibah Nasrullah Nasrullah Nasution, Rizki Hasanah Nazri, Nazri Nesvita, Erma Ni Ketut Kariani Ni Luh Putu Herli Mastuti Ningrum Paramita Sari Nisa, Yushfa Yufrida Nazzun Nopitasari, Hayu Sukowati Novianti, Sherly Nur Arisah Nur, Jumiati Nur, Putri Bella Aulia Nuraisyiah, Nuraisyiah Nurhasanah Nurhasanah Nurhayati Nurhayati Nurjannah Nurjannah Nurojiyah, Siti Nursyahran, Nursyahran NURUL AZIZAH Oppusunggu, Kamrul Ovinery, Amarsya Palupi, Novi Dwi Pande Made Dwijayasa Perdana Aditya Rahman PILLY, NASRI Pradipta, Dea Pratama, Mirza Z. Pratama, Mirza Zaka Pritasari, Octaverina Kecvara Purwitasari, Alief Ayu Putri, Choirinnisa Meilia Ayu Putri, Zakiyah Rahmah R. Hariyani Susanti Rachmawaty Rachmawaty, Rachmawaty Rachmayani, Ika Rafiqa, Syarifa Rahmatullah Rahmatullah Rangga, Agnesi Rawaty, Iis Retty Ratnawati Riesso, Andi Sawe Rifdan . Rinik Eko Kapti, Rinik Eko Rista Nikmatu Rohmah, Rista Nikmatu Rizki, Yeni Aprila Roswati, Roswati rubino, rubino Rusdi Rusdi Rusdin Rauf Rusiyati Rusiyati S, St.Sukmawati. S., Salmin Safrina Dewi Ratnaningrum, Safrina Dewi Sail, April SALEH, MAHADIN Saputri , Wahyu Eka Sari, Riana Trinovita Sari, Tita Luthfia Sarini Yusuf sastrariah, sastrariah Seno Andri Seriana, Seriana Setyawati Soeharto, Setyawati Setyowati, Anisa Siregar, Batumahadi Siti Helmyati Siti Rahmawati Sitti Rahma, Sitti Situmorang, Melani Chysti sofia, nur zarit Solikhah, Lilik Sofiatus Solly Aryza Sri Dwiyanti Sri Wahyuni Sriati Sriati, Sriati Subandi Subandi Subandi Subandi Sudia, LaBaco Sugeng, Santoso Suharlan, Didy Sukirman Nurdjan, Sukirman Sukmawati Paju Sulistiani, Ita Sulistomo, Hikmawan Wahyu Sumriah, Sumriah Supriadi, Dede Supriatno, Supriatno Sutinah Made, Sutinah Sutrisna, Sela Sutrisno, Franky Suwito Eko Pramono T, Angriani Thamrin Tahir Titin Andri Wihastuti Toto, Herenal Daeng Triastuti, Maya Indah Tuti Afriani Tuti Supatminingsih Ulandari, Ratni Utami, Cleofatra Wahab, M. Fiqriansyah Wahida Wahida Wahono, Cesarius Singgih Wandini, Rora Rizky Wardani, Dewi Azar Nuria Wardha Jalil Warneri . Wilujeng, Biyan Yesi Wirtati, Ira Wisnu Barlianto Wiyasa, I Wayan Arsana Wulan Purnama, Wulan Yanti, Novita Virda Yosfi Rahmi Yulian Wiji Utami Yulianadewi, Ina Yundari, Yundari Yunding, Muhrawi Zaenal Kusuma Zakia Umami zulfikar, Achmad Jusuf Zulkifli Lubis