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All Journal Buletin Peternakan SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN VALENSI Cakrawala Pendidikan Kinesik Jurnal Teknik Sipil Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) IJOG : Indonesian Journal on Geoscience Jurnal Komunikasi Jurnal Dakwah Tabligh Jurnal Diskursus Islam Jurnal Produksi Tanaman FIAT JUSTISIA: Jurnal Ilmu Hukum Erudio: Journal of Educational Innovation Global Strategis Journal of Agromedicine and Medical Sciences JURNAL ILMIAH PENDIDIKAN FISIKA AL BIRUNI Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Biology, Medicine, & Natural Product Chemistry Dinamika Jurnal Pendidikan Dasar Jurnal Fisika FLUX Sociae Polites: Majalah Ilmiah Sosial-Politik JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Kimia Riset Public Health of Indonesia Al Qodiri : Jurnal Pendidikan, Sosial dan Keagamaan Jurnal Akta Jurnal Komunikasi Ikatan Sarjana Komunikasi Indonesia Turbo : Jurnal Program Studi Teknik Mesin Chimica et Natura Acta Jurnal Bina Mulia Hukum Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Kesehatan Komunitas Cyberspace: Jurnal Pendidikan Teknologi Informasi ELS Journal on Interdisciplinary Studies in Humanities Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Andalas Journal of International Studies Media Kesehatan Politeknik Kesehatan Makassar YUSTISI Jurnal Pengabdian Magister Pendidikan IPA Jurnal Pensil : Pendidikan Teknik Sipil Jurnal Ilmu Fisika Iqtishoduna: Jurnal Ekonomi Islam Jurnal Sehat Mandiri Sang Pencerah: Jurnal Ilmiah Universitas Muhammadiyah Buton MEDIALOG: Jurnal Ilmu Komunikasi Communicology: Jurnal Ilmu Komunikasi Indonesian Journal of Community Services Kappa Journal Warta Ikatan Sarjana Komunikasi Indonesia The Journal of Society and Media Silampari Jurnal Pendidikan Ilmu Fisika Progressive Law Review PEDAGOGIKA Acta Chimica Asiana Ekspresi dan Persepsi : Jurnal Ilmu Komunikasi ARIKA At-Tanzir : Jurnal Ilmiah Prodi Komunikasi Penyiaran Islam Medium : Jurnal Ilmiah Fakultas Ilmu Komunikasi Jurnal Teknik Industri Terintegrasi (JUTIN) Jurnal Ilmiah Ilmu Komunikasi Communique Jurnal Ilmu Sosial, Politik dan Pemerintahan Indonesia Berdaya Yustisi: Jurnal Hukum dan Hukum Islam Interference: Journal of Language, Literature, and Linguistics Jurnal Kesehatan Masyarakat Mulawarman (JKMM) Jurnal Pendidikan Vokasi Otomotif JURNAL STUDIA KOMUNIKA LEARNING : Jurnal Inovasi Penelitian Pendidikan dan Pembelajaran Wasilatuna: Jurnal Komunikasi dan Penyiaran Islam Komitmen : Jurnal Ilmiah Manajemen Mabny : Journal of Sharia Management and Business Jurnal Penelitian Inovatif Jurnal Abdimas Kartika Wijayakusuma Muhasabatuna: Jurnal Akuntansi Syariah Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Paradigma: Jurnal Ilmu Pendidikan dan Humaniora Munggai: Jurnal Ilmu Perikanan dan Masyarakat Pesisir Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Multidisiplin Madani (MUDIMA) Journal Of Human And Education (JAHE) Formosa Journal of Multidisciplinary Research (FJMR) TECHSI - Jurnal Teknik Informatika Seminar Nasional Pengabdian Kepada Masyarakat Journal of Innovation Research and Knowledge KAGANGA KOMUNIKA: Journal of Communication Science JUSTER: Jurnal Sains dan Terapan Makara Journal of Science Ahmad Dahlan Medical Journal Tepis Wiring : Jurnal Pengabdian Masyarakat Anoa: Journal of Animal Husbandry Jurnal Sains dan Teknologi Tadulako Education Journal: General and Specific Research Jurnal Ilmiah Hukum dan Hak Asasi Manusia Journal of Scientific Research, Education, and Technology Adabuna: Jurnal Pendidikan dan Pemikiran Jurnal Pendidikan Indonesia (Japendi) Indonesian Research Journal on Education Indonesian Journal of Advanced Research (IJAR) Jurnal Katalisator Al-Rasikh : Jurnal Hukum Islam Business and Investment Review Khidmatuna: Jurnal Pengabdian Masyarakat Jurnal Ilmu Komunikasi UHO : Jurnal Penelitian Kajian Ilmu Komunikasi dan Informasi Lontar Physics Today Adabuna: Jurnal Pendidikan dan Pemikiran Mandub: Jurnal Politik, Sosial, Hukum dan Humaniora Banda Historia: Jurnal Pendidikan Sejarah dan Studi Budaya Causa: Jurnal Hukum dan Kewarganegaraan Infolitika Journal of Data Science GEMBIRA (Pengabdian Kepada Masyarakat) Jurnal Pengabdian Masyarakat dan Riset Pendidikan Jurnal Media Akademik (JMA) International Journal Multidisciplinary Jurnal Hukum dan Pembangunan Journal of Regional Development and Technology Initiatives Multidisciplinary Journals Journal of Islamic Contemporary Accounting and Business Jurnal Abdi Negeriku International Journal of Research in Counseling Aliansi: Jurnal Hukum, Pendidikan dan Sosial Humaniora Mahkamah: Jurnal Riset Ilmu Hukum Jurnal Abdita Naturafarm J+Plus: Jurnal Mahasiswa Pendidikan Luar Sekolah UNM Journal of Technology and Vocational KAMBOTI : Jurnal Sosial dan Humaniora Kimia Padjadjaran Eksplorium : Buletin Pusat Pengembangan Bahan Galian Nuklir Civic-Culture: Jurnal Ilmu Pendidikan PKn dan Sosial Budaya Nemui Nyimah
Muhammad Farid
Institut Agama Islam Darullughah Waddawah
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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PERAN ALUMNI KOMUNIKASI DAN PENYIARAN ISLAM DI INDUSTRI MEDIA PENYIARAN DI MAKASSAR Razak, Nur; Sultan, Moehammad Iqbal; Muhammad Farid; Zulfikri Fajar Fahd
AT-TANZIR: JURNAL ILMIAH PRODI KOMUNIKASI PENYIARAN ISLAM Vol. 15, No. 2 (Desember 2024)
Publisher : Sekolah Tinggi Agama Islam Negeri (STAIN) Teungku Dirundeng Meulaboh Aceh Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47498/tanzir.v15i2.3527

Abstract

Industri media penyiaran di Indonesia terus berkembang pesat, menuntut tenaga kerja yang kompeten dan terampil. Lembaga pendidikan seperti KPI berperan penting dalam menyiapkan lulusan yang siap berkiprah dalam kemajuan industri media penyiaran terkhusus di Makassar. Namun, sejauh ini belum banyak penelitian yang mengkaji secara mendalam tentang peran alumni KPI di media penyiaran di Makassar. Untuk itu, tujuan dan maksud penelitian ini adalah untuk menganalisis peranan Alumni KPI di media penyiaran serta strategi alumni KPI dalam mempersiapkan diri untuk berkiprah di industri media penyiaran. Jenis penelitian yang digunakan adalah metode penelitian kualitatif. Hasil analisis data disajikan ke dalam bentuk uraian narasi. Hasil penelitian ini adalah peranan alumni KPI sangat penting karena alumni KPI memiliki basic krusial sehingga membuat para alumni KPI mampu bersaing dibidang industri penyiaran. Adapun faktor pendorong alumni KPI dalam berkiprah diindustri media penyiaran yakni memiliki passion di antaranya kemampuan, kemauan, menguasai tiga skil inti (broadcasting, writing, dan public speaking), dan berani mengambil peluang. Sedangkan penghambatnya yaitu kurang memiliki skill yang baik, persaingan antara wanita yang non berhijab yang lebih didahulukan, kurangnya informasi dan pegetahuan. Namun secara empiris alumni KPI sangat berpengaruh bagi industri dunia penyiaran karena telah mengetahui dan menguasai tiga aspek penting dalam media penyiaran.
THE ROLE OF COMMUNITY COUNSELORS IN INCREASING CLIENTS SELF-CONTROL AT THE CORRECTIONAL CENTER CLASS I BANDAR LAMPUNG: THE ROLE OF COMMUNITY COUNSELORS IN INCREASING CLIENTS SELF-CONTROL AT THE CORRECTIONAL CENTER CLASS I BANDAR LAMPUNG Ariyanti, Luh Yuke; Dona Raisa Monica; Muhammad Farid
Progressive Law Review Vol. 7 No. 1 (2025): APRIL 2025
Publisher : Faculty of Law-Universitas Bandar Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36448/prolev.v7i1.222

Abstract

The Correctional Center class I Bandar Lampung, hereinafter referred to as Bapas, plays an important role in providing guidance to juvenile and adult clients so that the clients can live well in society. Bapas itself has the main task and function of being a community supervisor who has the responsibility of guiding WBP (Correctional Prisoners) based on the rules and regulations of the institution that are still valid. The aim is to guide WBP to have awareness in order to make themselves better and not commit criminal acts that they have committed before or more severe criminal acts. The role of Community Counselors is carried out in the form of tasks and functions of community counseling in the stages of the criminal justice system for everyone who commits a crime, starting from the pre-sentencing and post-sentencing stages. During the pre-sentencing and sentencing process, Community Counselors are tasked with conducting community investigations and assisting ABH (Children in conflict with the law) as well as adult prisoners or adult clients.
Prediction of Artocarpus altilis Potential as an Anti Breast Cancer by Inhibiting EGFR: a Molecular Docking Study Farid, Muhammad; Rastrani, Ardestya; Rahma, Adinda Aulia; Ramadhania, Widya Aryana
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.199-204

Abstract

Reseptor Faktor Pertumbuhan Epidermal (EGFR) merupakan target penting dalam terapi kanker payudara, mengingat perannya dalam proliferasi, motilitas, dan invasi sel tumor melalui jalur pensinyalan penting seperti Ras-MAPK dan PI3K/Akt. Penelitian ini mengeksplorasi potensi senyawa aktif Artocarpus altilis (AA), yang kaya akan flavonoid, sebagai alternatif kemoterapi. Metode docking molekular digunakan untuk memprediksi interaksi antara senyawa AA dan protein EGFR (PDB ID: 2J6M). Validasi docking menunjukkan nilai RMSD sebesar 0,854 Å, yang menunjukkan akurasi tinggi. Asam ellagic menunjukkan afinitas pengikatan terbaik (-8,4 kkal/mol), diikuti oleh Quercetin (-7,3 kkal/mol), Katekin, dan Epikatekin (-7,2 kkal/mol). Analisis residu mengungkapkan bahwa MET793 memainkan peran kunci dalam stabilitas interaksi. Visualisasi interaksi dan prediksi ADMET menunjukkan bahwa sebagian besar senyawa memenuhi Aturan Lima Lipinski, tanpa risiko hepatotoksisitas atau mutagenesis. Senyawa potensial seperti Quercetin dan Epicatechin menunjukkan kinerja yang sebanding dengan doxorubicin, tetapi dengan potensi efek samping yang lebih rendah. Hasil ini memperkuat peran senyawa alami sebagai kandidat untuk terapi kanker yang ditargetkan pada EGFR, yang menyediakan dasar untuk pengembangan obat antikanker yang lebih aman dan lebih efektif.
Early Islam in Nusantara: The First Trace of Islam through the Spices Trade Farid, Muhammad
Adabuna : Jurnal Pemikiran dan Pendidikan Vol 1 No 1 (2021): December
Publisher : Program Pascasarjana Institut Agama Islam (IAI) Darullughah Wadda'wah Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstract The history of the entrance of Islam became the most important and the most obscure event in the discourse of Indonesian history. The authors note two fundamental problems concerning this "Early Islam": terminological problems and geographical problems. By using structural approach and through the procedures of Heuristics, Source Criticism, Interpretation, and Historiography, the study found that Islam came to Banda-Maluku Islands since the first year of Hijri calendar, or between the 7th and 8th century, practiced by the nomadic Muslim travelers in several important cities, Banda and Ternate. Secondly, nutmegs and cloves were the main commodity trade that has captivated Muslim merchants to come to Banda Islands in the early period, thus, it made the region as the gate of Islam entrance in North Indonesia. Finally, the process of Islam institutionalization in the harbor cities such as Banda, Ternate, and Hitu reached its peak in the 13th and 14th century. This was evidenced by the changes of Kolano to Sultanate, the establishment of Islamic Confederation in Hitu and Banda, and the formation of OK (Orang Kaya, literally means “rich people”) “organization”—an organization of the rich people which regulated the trade issues. These findings are considered to make Banda Naira (Maluku) as the "new challenger" in the discourse of Early Islam in Indonesia. Keywords: Early Islam, Spices Trade, Nusantara
ANALISIS TINGKAT KERUSAKAN KOMPONEN SISTEM AIR CONDITIONER PADA KENDARAAN RINGAN Farid, Muhammad; Annis, Muh; Haruna, Haruna
Jurnal Pendidikan Vokasi Otomotif Vol. 7 No. 2 (2025): (Mei)
Publisher : Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jpvo.v7i2.85084

Abstract

Penelitian ini adalah penelitian deskriptif kuantitatif yang bertujuan untuk mengetahui jenis perawatan/perbaikan yang dilakukan pada bengkel Air Conditioner (AC) mobil dan mengetahui tingkat kerusakan komponen sistem AC pada kendaraan ringan. Variabel pada penelitian ini adalah kerusakan komponen sistem AC pada kendaraan ringan. Penelitian ini berlokasi pada tiga bengkel di kota Makassar, yaitu bengkel Pemeliharaan dan Perbaikan Toyota cabang Urip Sumuharjo, bengkel Mahaputra dan bengkel Kharisma AC. Teknik pengumpulan data menggunakan observasi dan dokumentasi. Teknik analisis data menggunakan analisis statistik deskriptif. Berdasarkan hasil penelitian diperoleh perawatan/perbaikan yang dilakukan pada bengkel AC mobil yaitu pengecekan dan perawatan sistem AC, penggantian dan penambahan refrigeran, penggantian saringan blower AC, pembersihan ruang kabin (fogging), penggantian kompresor, penggantian kondensor, penggantian katup ekspansi, penggantian evaporator, dan penggantian receiver dryer. Berdasarkan hasil analisis statistik deskriptif diperoleh tingkat kerusakan komponen sistem AC pada kendaraan ringan dalam kategori yang beragam. Tingkat kerusakan komponen sistem AC yaitu penggantian kompresor kategori “sangat tinggi”, penggantian evaporator kategori “tinggi”, penggantian receiver dryer kategori “cukup tinggi”, penggantian katup ekspansi kategori “cukup rendah” dan penggantian kondensor kategori “rendah”. Kata Kunci: Perawatan/perbaikan, Tingkat Kerusakan, Air Conditioner System.
Faktor-Faktor yang Mempengaruhi Kinerja Karyawan di Sektor Perbankan : Studi Literatur Kualitatif Zahroh, Andini Alfi; Rahmawati, Lusy; Farid, Muhammad; Fitria, Nabilatul; Putra, Riyan Sisiawan
Business and Investment Review Vol. 3 No. 3 (2025)
Publisher : CV. Lenggogeni Data Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61292/birev.175

Abstract

This study aims to analyze the factors that influence employee performance in the banking sector through a systematic literature review approach. The main focus of the study is three important variables, namely work motivation, leadership style, and work discipline, which have been widely studied in various national and international journals related to employee performance in the banking industry. The SLR method is used to collect, review, and synthesize findings from 15 relevant journals, thus providing a comprehensive picture of the relationship between the three variables and employee performance. The results of the analysis show that work motivation has a significant positive effect on performance, where motivated employees are more productive and contribute optimally. An effective leadership style also plays an important role in improving performance by creating a conducive work environment and supporting employee development. In addition, work discipline has been proven to be a supporting factor that strengthens the consistency and quality of employee work. This study suggests that banking management should focus on improving these three aspects in order to maximize employee performance and achieve organizational goals effectively. The implications of this study can be the basis for human resource development strategies in the banking sector. ABSTRAK Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi kinerja karyawan di sektor perbankan melalui pendekatan studi literatur sistematis (Systematic Literature Review). Fokus utama penelitian adalah tiga variabel penting, yaitu motivasi kerja, gaya kepemimpinan, dan disiplin kerja, yang telah banyak dikaji dalam berbagai jurnal nasional dan internasional terkait kinerja karyawan di industri perbankan. Metode SLR digunakan untuk mengumpulkan, mengkaji, dan mensintesis temuan dari 15 jurnal relevan, sehingga memberikan gambaran komprehensif mengenai hubungan antara ketiga variabel tersebut dengan kinerja karyawan. Hasil analisis menunjukkan bahwa motivasi kerja memiliki pengaruh positif signifikan terhadap kinerja, di mana karyawan yang termotivasi lebih produktif dan berkontribusi optimal. Gaya kepemimpinan yang efektif juga berperan penting dalam meningkatkan kinerja dengan menciptakan lingkungan kerja yang kondusif dan mendukung pengembangan karyawan. Selain itu, disiplin kerja terbukti menjadi faktor pendukung yang memperkuat konsistensi dan kualitas kerja karyawan. Penelitian ini menyarankan bagi manajemen perbankan untuk fokus meningkatkan ketiga aspek tersebut guna memaksimalkan kinerja karyawan dan mencapai tujuan organisasi secara efektif. Implikasi penelitian ini dapat menjadi dasar strategi pengembangan sumber daya manusia di sektor perbankan. Kata kunci: kinerja karyawan, motivasi kerja, gaya kepemimpinan, disiplin kerja.
Empowerment Model on Adolescent Social Capital for Smoking Cessation Behavior in Sumenep, East Java Riyadi, Sujono; Utami, Khristina Dias; Al Madury, Shalahuddin; Farid, Muhammad
Public Health of Indonesia Vol. 11 No. 2 (2025): April - June
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i2.984

Abstract

Background: Smoking is one of the risk factors for increasing morbidity and premature mortality worldwide. The large number of teenagers who smoke makes smoking the second largest contributor to global disability adjusted for life years with 148 million cases each year. Objective: This study aims to test a social empowerment model for adolescents to quit smoking, by exploring the influence of variables related to smoking cessation behavior among adolescents. Method: This study used a descriptive analytical design with a cross-sectional approach, involving 200 adolescents aged 12-25 years in Sumenep Regency, Madura. The structured questionnaire used to collect data has been validated. The analysis was carried out with descriptive statistics and path analysis using the STATA 13 to evaluate the effect of variables on smoking cessation behavior. Results: The study showed that out of 200 adolescents, 66% had a strong intention to quit smoking. Positive attitudes, subjective norms, and perceived behavioral control significantly influenced the intention to quit smoking. Adolescents with high knowledge about the dangers of smoking and strong social capital from peers also showed higher intentions. Path analysis indicated that the intention to quit smoking was the main mediator by the influence of attitudes, norms, and knowledge on smoking cessation behavior, with a p-value <0.001 indicating high significance. Conclusion: The smoking cessation behavior adolescents is influenced by intention to quit smoking, positive attitudes, subjective norms, perceived control, and knowledge about the dangers of smoking. Social capital from peers plays an important role in increasing this intention. The implications of the results of this study emphasize the need for education-based interventions and social support to reduce smoking habits among adolescents. Keywords: Social capital; adolesent;  smoking cessation
Improving Product Quality through the Implementation of Good Manufacturing Practices and Vacuum Packaging in Smoked Catfish Businesses in Pasaman Setiawan, Rizki Dwi; Ananda, Ananda; Sandy, Ikhlas Pratama; Juliyarsi, Indri; Melia, Sri; Vebriyanti, Ely; Sukma, Ade; Aulia, Surya; Putri, Annisa; Rifki, Adam Muhammad; Sari, Deta Yosfa; Salsabila, Andhini Aulia; Farid, Muhammad; Hasanah, Zahratul
Indonesian Journal of Community Services Vol 7, No 1 (2025): May 2025
Publisher : LPPM Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijocs.7.1.85-92

Abstract

The production of smoked catfish in Pasaman Barat faces several challenges, including traditional smoking processes that lack the implementation of Good Manufacturing Practices (GMP), inadequate packaging and labeling, and limited marketing strategies. These conditions result in inconsistent product quality, a short shelf life, and low market competitiveness. This community service program aims to improve the product quality and sustainability of the Gusni Afrida MSME partner through the application of GMP, enhanced packaging techniques, and the development of digital marketing strategies.  The methods employed include training in GMP implementation, vacuum packaging techniques, labeling, replacement of equipment compliant with GMP standards, and mentoring in GMP applications. The program enhances the partner's understanding of GMP, vacuum packaging techniques, labeling, production management, and digital marketing, accompanied by the practical implementation of GMP. This involves the use of equipment that meets GMP standards, employing proper production personnel attributes, vacuum packaging techniques, and attractive product labeling. In addition, e-commerce-based marketing broadens market access.  Implementation of this program is expected to positively impact the quality, efficiency, and competitiveness of the partner's products. The adoption of GMP and modern marketing strategies can serve as models for the development of small businesses in the local food industry.
Analisis Penerapan Peraturan Mahkamah Agung Nomor 1 Tahun 2024 Terhadap Anak dan Lansia yang Melakukan Tindak Pidana Ringan Serly Rahmayati; Erna Dewi; Muhammad Farid
Mahkamah : Jurnal Riset Ilmu Hukum Vol. 2 No. 3 (2025): Juli : Mahkamah : Jurnal Riset Ilmu Hukum
Publisher : Asosiasi Peneliti dan Pengajar Ilmu Hukum Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/mahkamah.v2i3.877

Abstract

Law enforcement against minor crimes committed by children and the elderly often causes public dissatisfaction because it is considered to not take into account the principles of justice and benefit. To answer this problem, the Supreme Court issued Supreme Court Regulation (Perma) Number 1 of 2024 concerning Guidelines for Adjudicating Criminal Cases Based on Restorative Justice. This study raises two main problems: (1) How is Perma Number 1 of 2024 applied to children and the elderly who commit minor crimes? and (2) What are the inhibiting factors in its implementation? The purpose of the study is to analyze the implementation of the Perma and identify the obstacles faced. The methods used are normative juridical and empirical juridical, with a statutory, case, and conceptual approach. Data collection was carried out through document studies and interviews with practitioners and academics. The results of the study show that Perma Number 1 of 2024 provides space for resolving minor criminal cases in a more humane manner through restorative justice. However, its implementation still faces obstacles, including the lack of understanding of law enforcement officers, limited supporting facilities, and resistance from some communities and victims who still choose the formal legal process. In conclusion, although this Perma provides a great opportunity for peaceful resolution, its implementation requires commitment from all parties. It is recommended that there be increased training and socialization for law enforcement officers, provision of penal mediation facilities, and additional regulations to strengthen protection for children and the elderly as vulnerable groups.
Unraveling the Therapeutic Potential of Andrographis paniculata for Tuberculosis: Molecular Docking Study Farid, Muhammad; Al Madury, Shalahuddin; Muslim, Ahmad Suriyadi; ‘Aini, Zakiyyah Qurrotul
Jurnal Kimia Riset Vol. 10 No. 1 (2025): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v10i1.69932

Abstract

Tuberculosis (TB) remains a global health challenge with increasing drug resistance. This study aims to explore the potential of Andrographis paniculata as an alternative anti-TB therapy through an in silico approach. The study was conducted using the molecular docking method using Biovia Discovery Studio, AutoDock 1.5.7, and ChemDraw 3D software. The target proteins analyzed were 1TYP and 3R6C. which play a role in the biosynthesis of Mycobacterium tuberculosis cell walls. The docking results showed that dehydroandrographolide and neoandrographolide compounds have lower binding energies than ethambutol, with ΔG values of -9.54 kcal/mol and -9.04 kcal/mol at 3R6C, respectively. Stable hydrogen and non-hydrogen interactions indicate a stronger inhibitory potential against protein targets. Pharmacokinetic analysis through SwissADME and PKCMS confirmed that this compound meets Lipinski's Rule of 5 criteria, and has lower toxicity compared to conventional TB drugs. Thus, this study provides new insights into the development of natural compound-based TB therapy, which is potentially more effective and has minimal side effects. Further studies are needed to confirm the activity of this compound through in vitro and in vivo tests.
Co-Authors 'Aini, Zakiyyah Qurrotul -, Wahyuddin . NURFAIDA A.MUHAMMAD SYAFAR Abd Hakim, Abd Abdul Rouf Abdullah, Adnan Abdurrohman Abidin, Habibi Ali Zainal Ade Sukma Adila Adilah, Dzulkahfi Zaki Adrian, Hanief Adriana Afifi, Abdullah A Agafanthy, Annysa Nur Agus Suandi, Agus Agustan Agustan, Agusta Ahdavia, Ikrima Ahmad Hafidz Lubis Ahmad Ihwanul Muttaqin Ahmad Ismail Ahmad Sjahriza Ahmad Suriyadi Muslim Ahmad Wahidiyat Haedar Akbar, Muh Akhmad Rifai Akhmad Syakur Aklya, Zatul Al Madury, Shalahuddin Alayda, Dinda Albani, Muhammad Syukri Alfiatus Syafa’ah Alfisar, Muhammad Alimuddin Unde, Andi Aliyah, Nelud Darajaatul Aljayanti, Malisa Almaduri, Shalahuddin Alqap, A. Sofwan F Amalia, Riska Dina Amelia Amelia Amellia , Rizky Ananda, Ananda Andi Alimuddin Unde, Andi Alimuddin Anggraeni , Fatimah Dewi Anggraeny, Nurwinda Anjani, Shelyna Dwi Annis, Muh Annisa Putri Apriliansyah, Feby Araminta, Widyadhari Yumna Ariani, Rizka Arianto Arianto -, Arianto Arif Rahman Saleh Arif, Rifda Mardian Arif, Rifda Nur Hikmawati Arifah, Sa'adatu Mukarromatil Ariyanti, Luh Yuke Arrahman, Naufal Arsi, Sefti Dini Arwani, Nurindah Aryani Putri, Belita Asari, Hafizh Ihsan Asep Irfan Asna, Saifal Asoka, Shadila Fira Asti Widuri, Asti Aulia, Surya Awisarita, Wiwara Ayu, Ratih Kusumaning Azami, Evan Aziza, Zahra Ifma A’yun, Qurroti Badrunanto, Badrunanto Bambang Setiawan Basuki, Triyono BHAKTI KARYADI Bonewati, Yulia Irwina Br Munthe, Arta Salesta Budi Rizki Husin Budi Rizky Husin Burhanuddin, Aang Dailami - Darmadi Deden Saprudin Dellia Maulidar Deni Achmad Deni Achmad Depri Liber Sonata Devicawati, Devicawati Dewi, Fitria Puspita Diah Gustiniati Maulani Diah Gustiniati Maulani Dian Atmasani Diansyah P, Ramadani Fitra Dini, Wa Dona Raisa Monica Dona Raisa Monica Dwi Anggraini Dwi Utami Dwinta Yulyanti Dwitawati, Ima Edla, Zalza Junior Efilda, Adila Putri Eko Raharjo Elmaningtyas Zahro, Tarisha Emilia Susanti Endang Widi Winarni Eniyati Eniyati, Eniyati Erna Dewi Evendi, Wakid FA, A. Sofwan Fahrizal Hazra Fardiansyah, Ahmad Irzal Fardila, Mita Farid Firmansyah Farida Yunita Fatimah, Jeanny Mariah Fatkhurrochman, Fatkhurrochman Fauziah Lubis FEPY SUPRIANI Fikriyyah, Zakiyatul Firganefi Firganefi Firganefi Firganefi Firganefi Fitrah, Andi Nur Fitria, Eddwina Aidila Fitria, Nabilatul Gani, Rasni Gendis Azhara Nuzwa Ginting, Mamanda Syahputra GS, R. Haryo Dewanto Hafid Ulinnuha Hamid, Abd. Rahman Hamka Hamka Hamka, Hamka Hana, Mifta Harlina Harlina Haruna, Haruna Hasanah, Zahratul Hasfi, Wirda Tri Hasrullah Hastangka Haufi Sukmamedian Helmi, Imra Atun Hendri Hestiawan Hendriko Henny Johan Henny Purwaningsih Herni HERNI, HERNI Hidayah, Natasya Erliana Hidayanti, Awaliyah Ramadhani Hidayatullah, Indra Hutagalung, Naomi Maynarti I Wayan Thariqy Kawakibi Pristiwasa Ibrahim, Rayes Igaa Noviekayati, Igaa Ihya' Ulumuddin Ikhlas Pratama Sandy Ikhwan, Hady Ilham Ilham Inawaty Sidabalok, Inawaty Indri Juliyarsi Indro Kirono Irmanida Batubara ISKANDAR Isnaini, Banun Intan Isrida Yul Arifiana ITA PUSPITASARI Jaka Rachmadetin Januarti, Rasti Putri Jumadin ., Jumadin Junaidi Salat Kahar Kamal, Sainal Edi Karmila, Andi Karnay, Sudirman Kasim, Sri Khairul Amri Khairul Amri Khairun Nisa Khoirudin, Ahmad Khristina Dias Utami Kirana, Assa Aulia Kris Wijoyo Soepandji Kusmana, Friska Sundari Laksmana, Roza Indra Latifah, Siti Nur Latifani, Arda Aprilia Latuapo, Abdullah Layaali, Khairul Lindung Zalbuin Mase Lindung Zalbuin Mase, Lindung Zalbuin Lubis, Fauziah M Anlian Fanza Ghifari M. JAYA ADI PUTRA, S.Si, M.Pd, M. JAYA ADI Majduddin, Muhammad Makkulau, Al Fareidza Zakaria Mandra, Muhammad Ahsan S Mansyur Mansyur Marmi Marmi Maroni Maroni Maryam Maryam Maryam Maryam, Juniarti Masduhan Khoiri Masyhuri, Muhammad Mau, Muliadi Maulana, Putri Mauliatun Nisa Maulidia, Riza Mauly Nadia Maya Shafira Meidiantama, Refi Melati, Inka Sukma Melia, Sri Membele, Tresna Seplinawati Misliniyati, Rena Moch. Mahsun Mochammad Dawam Maghfoer Moh. Thamdzir Mohammad Apriniyadi Mohammad Soleh Mualim Wijaya Muh. Akbar Muh.Akbar Muhammad Munir Muhammad Nadjib, Muhammad Muhammad Rifai Muhammad Syarifullah Muhammad Yahya Muhammad Yusron Maulana El-Yunusi Mujiono, Zuhair Sudrajat Tiyan Munawaroh, Silvia Murniarti, Rilda Muslem Muslem, Muslem Muslimin, Ikhwanul Mutiara Putri Nabila, Nabila Najira Amsi Nakashima, Satoru Nazila, Syifa Nevi Danila Ng, Khar Thoe Nikmah Rosidah Nikman Azmin Ningrum, Retno Amalia Ningsih, Flamita Putri Ningsih, Indah Putri Ningsih, Yuniati Nirwana Noer Aisyah Barlian, Noer Aisyah Noerpitasari, Erlina Nufus, Hidayati Nur Asnawi Nur, Erdi Nurdaida Nurfitra Yanto Nurhayani H. Muhiddin, Nurhayani H. Nurmitasari, Ainy Amiranti Nurul Izza AR Nusantara, Widya Nuzullah, Teuku Muhammad Faiz Oktaviana, Nandita Diah Onasis, Aidil Pane, Ratri Khaidir Praselanova, Reiza Prastiwi, Anisya Dwi Pratama, Lucky Febrian Putra Purnama Putra, Surya Jaya Puspitasari, Ita Putra, Surya Jaya Purnama Putri, Eka Susnita Putri, Rachma Greta Perdana Putri, Ratna Aprillia Eka R. Rusli Rahma, Adinda Aulia Rahmadani, Sandra Rahmawati, Lusy Rahmayani, Mentari Tri Indah Raissa Rahmah Ramadhania, Widya Aryana Rastrani, Ardestya Rasyda, Sofia Razak, Nur Refrizon Refrizon Rera Aga Salihat Rezaskov, Achmad Altariq Rifki, Adam Muhammad Rinaldy Amrullah Rini Fathonah Risdayanti, Risdayanti Risnaeni, Umi Suswati Riviwanto, Muchsin Riyan Sisiawan Putra Rizki Dwi Setiawan Rizkita, Leonny Dwi Rizqi Amaliyah, Angguliyah Rusdiah, Ratu Rustam, Tata Myranti S. Gonda, Meytri Safitri, Indah Saharuna, Saharuna Saleh, Nurming Salma Salma Salsabila, Andhini Aulia Samputri, Salma Samuel Patra Ritiauw Sandra Arifin Aziz Sania, I Luh Devi Sanjaya, Raju Saputra, Dwi Luhur Ibnu Saputra, Feri Sarah Sarah, Sarah Sari, Deta Yosfa Sarwadhamana, Raden Jaka Sasmita, Novi Reandy Satrio, Garin Ahmad Sekani Niriyah Selfina, Tjali, Ernest Sennahati Septeddy Endra Wijaya Septriani, Endang Setiowati Serly Rahmayati Setyanto Tri Wahyudi Shafariana Shafariana Shafira, Anisya Elsa Shinta Nuriah Ramadani Sholawati, Putri Mustika Sihotang, Juan Carlos Siti Maryama, Siti Siti Ruqaiyah Baharuddin Sitti Saenab, Sitti Slamet Widodo Soadiking, Misbar Sonni, Alem Febri Suci, Laksmi Nurul Sugiono, Rudi S Sujono Riyadi Sukmadewi M, Fitrah Sulhani, Sulhani Sultan, Moehammad Iqbal Suroso Suroso Suroso Suswati Risnaeni, Umi Sutipyo R dan Amrih Latifah, Sutipyo R dan Syakir, Fakhrus Syakur, Sultan Abdus Syarbini, Nuzul Syavira, Alyfia Talib, Wasir Tamaulina Br Sembiring Tamza, Fristia Berdian Taopik Ridwan Tatik Wardiyati Taufik Sepdi Ariananda Taufiq, Umar Temarwut, Rahma Teuku Faisal Fathani Tri Kanti, Tri Tri Wijayanti Trijayanti, Dita Triwahyuni Wardhany Tuti Bahfiarti Tuti Bahfiarti Ulhaq , Muhammad Zia Ulhaq, Muhammad Zia Umi Suswati Risnaeni Umila, Titin Urmila, Titin Vebriyanti, Ely Vivin Tri Kurniasari Wabdillah Wabdillah, Wabdillah Wahidiyat, Ahmad Wahyuddin Widiana, Riska Dina Wisanti, Eka Wiwik Handayani Wulan Tri Wahyuni Yahya Yahya, Ismayanti Yeza Febriani Yulia Irwina Bonewati Yuniar, Hesti Firza Yuniningsih Yuniningsih Yuska, Shaldhan Bayu Yusminah Hala Zafitrah Zahara, Nadia Zahroh, Aminatuz Zahroh, Andini Alfi Zaila Sari Zakiyyah Qurrotul ‘Aini Zercy Nurjannah Zikra Hayati Zulfikri Fajar Fahd Zuliantoni, Zuliantoni