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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Dasar Jurnal Ekonomi & Bisnis PNJ (JEKBIS PNJ) Jurnal Teknik Kimia USU BIOTROPIA - The Southeast Asian Journal of Tropical Biology Jurnal Dakwah Tabligh Shaut Al-'Arabiyah Jurnal Imejing Diagnostik Jurnal Pendidikan Agama Islam Wahana Teknik Sipil: Jurnal Pengembangan Teknik Sipil IDEAS: Journal on English Language Teaching and Learning, Linguistics and Literature Journal of Geoscience, Engineering, Environment, and Technology Majalah Kesehatan FKUB Akademika : Jurnal Manajemen, Akuntansi, dan Bisnis Jurnal Pemberdayaan Masyarakat Madani (JPMM) Journal Of Vocational Health Studies qolamuna : Jurnal studi islam Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat ELSE (Elementary School Education Journal) : Jurnal Pendidikan dan Pembelajaran Sekolah Dasar Jurnal Teknologi Agro-Industri Pendas : Jurnah Ilmiah Pendidikan Dasar Jurnal Ilmiah Kebidanan Jurnal Hukum Samudra Keadilan Owner : Riset dan Jurnal Akuntansi Acta Biochimica Indonesiana Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Golden Age: Jurnal Ilmiah Tumbuh Kembang Anak Usia Dini Jurnal Loyalitas Sosial: Journal of Community Service in Humanities and Social Sciences Al-Asalmiya Nursing: Journal of Nursing Sciences Jurnal Informasi dan Teknologi Al-Kharaj: Journal of Islamic Economic and Business Jurnal Riset Akuntansi Politala Publik: Jurnal Manajemen Sumber Daya Manusia, Administrasi dan Pelayanan Publik Didaktik : Jurnal Ilmiah PGSD STKIP Subang Jurnal Perangkat Lunak Jurnal Pengabdian Masyarakat Asia Nivedana : Jurnal Komunikasi dan Bahasa Indomera : Jurnal Magister Manajemen International Journal of Finance Research Jurnal Insan Farmasi Indonesia JURNAL MASYARAKAT NEGERI ROKANIA Azzahra : Jurnal Pendidikan Anak Usia Dini These proceedings represent the work of researchers participating in The International Conference on Elementary Education (ICEE) which is being hosted by the Elementary Education Study Programme School of Postgraduate Studies, Universitas Pendidikan Medical Journal of Al-Qodiri : Jurnal Keperawatan dan Kebidanan Indonesian Community Empowerment Journal Aquamarine (Jurnal FPIK UNIDAYAN) Arus Jurnal Pendidikan INTERNATIONAL JOURNAL OF CULTURAL AND SOCIAL SCIENCE Jurnal ABDIMAS Panrita ALMUJTAMAE: Jurnal Pengabdian Masyarakat Litera Kultura Improvement: Jurnal Manajemen dan Bisnis Jurnal Teknik Kimia USU Jurnal Hukum Legalita caXra: Jurnal Pendidikan Sekolah Dasar Al-Manahij : Jurnal Kajian Hukum Islam Nusantara Islamic Economic Journal Journal of Artificial Intelligence and Engineering Applications (JAIEA) BHAKTI PERSADA Jurnal Aplikasi IPTEKS (Journal of Applied Sciences and Technology) JURNAL AGROINDUSTRI HALAL ISTIQRA: JURNAL HASIL PENELITIAN International Journal of Public Health Excellence (IJPHE) Jurnal Komputer Teknologi Informasi Sistem Komputer (JUKTISI) Makara Journal of Science International Journal of Scientific and Professional Maternity and Neonatal : Jurnal Kebidanan Jurnal Pendidikan Transformatif Proceeding Muhammadiyah International Public Health and Medicine Conference PENDALAS: Jurnal Penelitian Tindakan Kelas dan Pengabdian Masyarakat Cessie : Jurnal Ilmiah Hukum International Journal of Community Service (IJCS) Jurnal Maritim Malahayati Jurnal Marine Inside JOURNAL OF ICT APLICATIONS AND SYSTEM Jurnal TLM Blood Smear Jurnal Adijaya Multidisiplin Jurnal Ilmu Ekonomi Journal of Research and Publication Innovation Indonesian Journal of Digital Public Relations Communication and Information Journal Indonesian Journal of Early Childhood : Jurnal Dunia Anak Usia Dini Al Fuadiy: Jurnal Hukum Keluarga Islam Central Publisher SINAU : Jurnal Ilmiah Pendidikan dan Pembelajaran RJOCS (Riau Journal of Computer Science) Presisi Jurnal Pengabdian Masyarakat AMMA : Jurnal Pengabdian Masyarakat Swakarya: Jurnal Penelitian Sosial dan Pemberdayaan Masyarakat JRUP: JURNAL REFERENSI DAN ULASAN PERPAJAKAN Recht Studiosum Law Review AL-SULTHANIYAH MULTIPLE: Journal of Global and Multidisciplinary MILRev: Metro Islamic Law Review Karimah Tauhid BEduManageRs Journal : Borneo Educational Management and Research Journal Al-Faiza: Journal of Islamic Education Studies Buletin Pengabdian Multidisiplin Jurnal Ilmu Komunikasi dan Sosial Politik GEMBIRA (Pengabdian Kepada Masyarakat) Darma Cendekia Journal of English Education BIMA Jurnal Bisnis dan Manajemen Jurnal Penelitian Pendidikan Indonesia (JPPI) Tabayyun : Journal of Islamic Studies Jurnal Intelek Dan Cendikiawan Nusantara Journal of Community Empowerment for Multidisciplinary (JCEMTY) Journal of Environmental and Development Studies Jurnal Pendidikan Ekonomi, Perkantoran, dan Akuntansi Jurnal Ilmiah Multidisiplin Ilmu Wealth: Journal of Islamic Banking and Finance Jurnal Industri Samudra Jurnal Pharma Bhakta Hayyan Journal Cakrawala: Jurnal Ekonomi, Manajemen dan Bisnis Journal of Transportation and Society Empowerment Indonesian Journal of Nautical Study IECON: International Economics and Business Conference Ruhui Rahayu: Jurnal Pengabdian Kepada Masyarakat Sevaka: Hasil Kegiatan Layanan Masyarakat Journal of Bio-molecule Research And Engineering Ahsan: Jurnal Ilmiah Keislaman dan Kemasyarakatan Media Pengabdian Kesehatan Indonesia Jurnal Ilmu Kesehatan Journal of Management Research and Studies Jurnal Ekonomi Syariah Mulawarman (JESM) Masterpiece Journal Society Service Insight Mitramas Jurnal Pengabdian dan Pemberdayaan Masyarakat Insight Journal Jurnal Ilmiah Mahasiswa & Penelitian Keperawatan Ekonosfera: Jurnal Ekonomi, Akuntansi, Manajemen, Bisnis dan Teknik Global Mitramas Jurnal Pengabdian dan Pemberdayaan Masyarakat Health Science & Biomedical Journal (HSBJ) Ar-Rasyid: Jurnal Publikasi Penelitian Ilmiah Annales Bogorienses Jurnal Bisnis dan Pembangunan Interdisciplinary Explorations in Research Journal (IERJ) Jurnal Ilmiah Akuntansi dan Keuangan (JIAN) Jurnal Ekonomi dan Bisnis (Ekobis-DA) Berita Biologi Abdimas Polsaka
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The Improvement of Fishbowl Technique on Tenth Grade Speaking Achievement Khair, Ummul; Telaumbanua, Faozatulo; Simorangkir, Eflin Novalynda; Fatimah; Lestari, Cicik Sri
Journal of English Education Vol. 1 No. 1 (2023): Journal of English Education
Publisher : CV. Doki Course and Training

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61994/jee.v1i1.148

Abstract

This research is concerned with the influence of the fishbowl on the speaking achievement of the tenth-grade students of SMAN 1 GAS INHIL RIAU. The objectives of this study were to find out: a) whether or not there was a significant influence on speaking achievement of the tenth-grade students of SMAN 1 GAS INGIL RIAU who were taught by using the fishbowl technique and those who were not, and b) whether or not there was a significant difference of speaking achievement between the tenth-grade students of SMAN 1 GAS INHIL RIAU who were taught by using fishbowl technique. The population was the tenth-grade students of SMAN 1 GAS INHIL RIAU in the academic year 2022/2023. The purposive Sampling technique was used to take a sample of this study which consisted of 80 students. This study used a quasi-experimental design, there were an experimental group and a control group. Both of them were given a pre-test and post-test (before and after treatment). In analysing the data, paired sample t-test and independent sample t-test would be applied. Based on statistical analysis, the result of paired sample t-test showed that t-obtained (14.835) > t-table (2.079) which means that the students’ speaking achievement was significantly influenced. Then the result independent sample t-test, the value of t-obtained (3.592) was higher than the critical value of t-table (2.079). It means that there was a significant difference between SMAN 1 GAS INHIL RIAU who were taught by using a fishbowl and those who were not.
Comparative Analysis of Implementation of Murabahah Bil Wakalah Contracts and Musyarakah Mutanaqisah Contracts for Sharia Financing Products Intansari, Anggita Isty; Fatimah
Wealth: Journal of Islamic Banking and Finance Vol. 1 No. 2 (2022)
Publisher : Faculty of Islamic Economics and Business, UIN Prof. K. H. Saifuddin Zuhri Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24090/wealth.v1i2.7070

Abstract

A home is a basic human need that plays an important role in the continuation of human life. The problem of housing and settlement has existed and will continue to exist in response to population growth, demographics and socio-economic needs. The high demand for housing and population growth provide opportunities for Islamic financial institutions to provide products that help people purchase housing. The purpose of this study is to determine the application of the Murabaha Contract and the Musharaka Mutanaqisah Contract and find a comparison of her two contracts in Islamic KPR funding. Knowing the mechanism and type of research represents field research. This research was conducted using qualitative methods with a descriptive approach. As a result of the research and analysis, it was found that the application of the Murabaha Bil Wakala Convention takes precedence over the Musharaka Mutanaqishah Convention. A comparison of the two loan agreements can then be viewed in terms of similarities and differences between the two agreements.
EFFECT OF INTERACTIVE PREGNANCY EDUCATION (IPE) ON STRESS LEVELS AMONG PRIMIGRAVID TRIMESTER III PREGNANT WOMEN Elli Hidayati; Syahrul Rauf; Mochammad Hatta; Sonny T. Lisal; Fatimah; Hamidah
Muhammadiyah International Public Health and Medicine Proceeding Vol. 4 No. 1 (2024): PROCEEDING MUHAMMADIYAH INTERNATIONAL PUBLIC HEALTH AND MEDICINE CONFERENCE - F
Publisher : Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61811/miphmp.v4i1.658

Abstract

The Infant Mortality Rate (IMR) is an indicator in determining the health level of a country. Infant mortality is caused by various health problems, especially since the gestation period, even starting before the gestation period. Stress during pregnancy affects the motor, cognitive and emotional development of the baby. This study aims to determine the effect of Interactive Pregnancy Education (IPE) on levels in third trimester primigravida pregnant women. This research is a quasi-experimental study using a nonequivalent control group design. This research was conducted in the Kemayoran and Cempaka Putih Community Health Centers in DKI Jakarta from December 2021 to completion. The samples were 30 third trimester primigravida pregnant women for the intervention and control groups. Data were analyzed using the Mann Whitney and Wilcoxon tests with SPSS 22 software. The results showed that there was a significant difference between the median stress scores in the control group before and after the median decreased after the intervention and the difference in the median stress scores before and after the intervention in the intervention group was greater than the control group, which decreased to 6.50. This shows that IPE is effective in reducing stress in pregnant women who have previously had stress with high stress scores.
Implementasi Digital Literasi dengan Menggunakan Aplikasi Canva dalam Pembuatan Buku Cerita Digital Pada Guru PAUD: Implementation of Digital Literacy Using the Canva Application in Making Digital Story Books for PAUD Teachers Fatimah; Hasiana, Isabella
Indonesian Journal of Early Childhood: Jurnal Dunia Anak Usia Dini Vol. 6 No. 2 (2024)
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijec.v6i2.3221

Abstract

The purpose of this study was to determine the implementation of digital literacy in Early Childhood Education. Teachers through the use of Canva application in making digital storybooks. The participants in this study were teachers in kindergartens in Waru sub-district, Sidoarjo. Data analysis used experimental quantitative statistical methods to compare differences between experimental and control groups. The results of the study are expected to provide insight into the improvement of digital literacy skills of early childhood teachers, the effectiveness of digital storybooks in improving early childhood children's concept understanding, and the collaborative impact of using technology in early childhood learning. The evaluation results show that digital storybooks created using Canva have a much higher visual and interactive appeal than conventional storybooks. On digital skills improvement, the t-test results showed a significant increase (p<0.05) in digital literacy skills in the experimental group after the training using Canva. The percentage of preschool children who liked digital storybooks reached 85%. Preschool children who interacted with digital storybooks showed a significant increase in concept understanding. ABSTRAK Tujuan penelitian ini untuk mengetahui implementasi digital literasi pada Guru PAUD melalui penggunaan aplikasi Canva dalam pembuatan buku cerita digital. Partisipan dalam penelitian ini adalah guru di TK di Kecamatan Waru, Sidoarjo. Analisis data menggunakan metode statistik kuantitatif eksperimen untuk membandingkan perbedaan antara kelompok eksperimen dan kontrol. Hasil penelitian diharapkan dapat memberikan wawasan tentang peningkatan keterampilan digital literasi guru PAUD, efektivitas buku cerita digital dalam meningkatkan pemahaman konsep anak-anak PAUD, dan dampak kolaboratif dalam penggunaan teknologi dalam pembelajaran anak usia dini. Hasil evaluasi menunjukkan bahwa buku cerita digital yang dibuat dengan menggunakan Canva memiliki daya tarik visual dan interaktif yang jauh lebih tinggi daripada buku cerita konvensional. Pada peningkatan keterampilan digital hasil uji t menunjukkan peningkatan signifikan (p<0.05) dalam keterampilan digital literasi pada kelompok eksperimen setelah pelatihan menggunakan Canva. Persentase anak-anak PAUD yang menyukai buku cerita digital mencapai 85%. Anak-anak PAUD yang berinteraksi dengan buku cerita digital menunjukkan peningkatan pemahaman konsep yang signifikan.
Systematic Literature Review on the Application of Convolutional Neural Networks for Rambutan Fruit Classification: Advances, Challenges, and Future Directions Meisaroh; Tantia Azzahra; Ismi Asmita; Fatimah; Rusmin Saragih
Journal of ICT Applications System Vol 3 No 2 (2024): Journal of ICT Aplications and System
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56313/jictas.v3i2.393

Abstract

Rambutan (Nephelium lappaceum L.) is a tropical fruit widely cultivated in Southeast Asia, including Indonesia. Manual classification of rambutan types and ripeness levels remains a challenge due to the high subjectivity and time-intensive nature of the process, particularly in large-scale agricultural operations. Convolutional Neural Network (CNN), a deep learning approach, offers significant potential in automating and improving the accuracy of fruit classification tasks by extracting complex visual features such as color and texture. This study employs a Systematic Literature Review (SLR) to evaluate the application of CNN in rambutan classification. Relevant research from 2019 to 2024 was analyzed to identify trends, accuracy levels, and challenges in utilizing CNN for this purpose. Results demonstrate that CNN achieves superior accuracy (>90%) compared to traditional methods like K-Nearest Neighbor (KNN). However, limitations include restricted dataset diversity and insufficient testing under real-world conditions. Recommendations for future research emphasize the need for larger, more diverse datasets and integration of additional media, such as spectral data and video, to enhance model robustness
Penguatan Pendidikan Karakter Melalui Kisah-Kisah Pahlawan Nasional: Telaah Kisah Pahlawan RA Kartini dan KH Hasyim Asy’ari Asad, Asad; Suyana, Nana; Fatimah; Ananto, Irfan
Darma Cendekia Vol. 3 No. 2 (2024): Darma Cendekia
Publisher : CV Buana Prisma Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60012/dc.v3i2.107

Abstract

Kegiatan Pengabdian kepada Masyarakat berupa Seminar Penguatan Pendidikan Karakter melalui Kisah-kisah Pahlawan Nasional bertujuan untuk membentuk peserta seminar berahlak mulia, beriman dan bertakwa kepada Allah SWT (religius), serta mencintai tanah air. Melalui kisah-kisah pahlawan tersebut tentu sangat efektif dalam menyampaikan pesan penting tanpa ada instruksi dari penyampai kisah. Peserta seminar adalah anak-anak pekerja migran Indonesia di Malaysaia dengan jenjang pendidikan dasar dan menengah di bawah Sanggar Belajar Yakesma Wiradamai Selangor Malaysia. Adapun metode yang digunakan dalam kegiatan ini adalah seminar dengan menyampaikan kisah-kasih pahwalan nasional R.A Kartini dan KH. Hasyim Asy’ari mulai dari biografi, pendidikan, dan nilai-nilai perjuangan sebagai bukti cinta tanah air. Hasil dari seminar ini mengingatkan sekaligus menguatkan peserta seminar dapat mengambil dan memperkuat nilai-nilai pendidikan karakter para pahlawan Nasional seperti religious, cinta tanah dair dan bekerja keras serta mereka dapat membayangkan situasi pada saat itu yang tentu lebih berkesan di hati.
Assessment of Genetic Diversity Using Morphological and Molecular Characteristics of Indonesian Zoysiagrass Genotypes Rahayu; Fatimah; Mo, Yang Geun; Bae, Eun Ji
HAYATI Journal of Biosciences Vol. 32 No. 1 (2025): January 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.1.263-277

Abstract

Zoysiagrass is warm-season turfgrass thriving in tropical regions. Despite the adaptive nature, the existence of Indonesian zoysiagrass as well as morphological and genetic characteristics are not available. Therefore, this study aimed to explore Indonesian zoysiagrass from western and eastern parts of the country, as well as its morphological and molecular characteristics. Morphological characteristics was conducted to measure vegetative and reproductive characters while genotyping was performed using 15 simple sequence repeat markers. Morphological characteristics cluster three major groups, namely Group 1 corresponded to short, shorter, and fine leaves. Group 2 corresponded to tall, longer, and fine leaves, fewer seeds, and short spikelet, while Group 3 corresponded to tall, long, and wider leaves, more seeds, and longer spikelet. The results showed that the expected heterozygosity (He = 0.256) was lower than homozygosity (Ho = 0.341). The high level of discriminating capacity, polymorphism, and informativeness of SSR marker was observed (Effective Multiplex Ratio = 4.20, Marker Index = 2.394, and Resolving Power = 1.574). Additionally, population structure generated two subpopulations. Group 1 corresponded to Z. japonica from Sumatera Island and mixed province while Group 2 corresponded to Z. japonica from Central Java and Bali with Z. japonica and Z. matrella from mixed province. In conclusion, the exploration of morphological and genetic diversity from Indonesian zoysiagrass provided useful insight for conservation and future breeding improvement.
Potential Probiotic Yeasts of the Pichia Genus Isolated from ‘Dadih’, a Traditional Fermented Food of West Sumatra, Indonesia Chihombori, Tatenda Calvin; Mustopa, Apon Zaenal; Astuti, Rika Indri; Mutiara, Ilma; Refli, Redoyan; Umami, Rifqiyah Nur; Fatimah; Irawan, Herman; Ekawati, Nurlaili; Trinugroho, Joko P; Akmaliyah, Rizna; Chairunnisa, Sheila; Amani, Febriyanti Nur; Manguntungi, Baso; Hertati, Ai; Mamangkey, Jendri
HAYATI Journal of Biosciences Vol. 32 No. 2 (2025): March 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.2.320-340

Abstract

Fermented buffalo milk, known as dadih, serves as a reservoir of potential probiotic yeasts. Over the past two decades, probiotic yeasts have gained increasing attention in both basic and clinical sciences due to their health benefits. This study aimed to isolate and characterize probiotic yeasts from dadih. Yeasts were isolated using yeast Extract, peptone, and dextrose (YPD) medium, and molecularly identified through 18S-rRNA sequencing. Probiotic potential was assessed by evaluating resistance to acidic pH, bile salts, proteolytic, lipolytic, and hemolytic activities. Secondary metabolites produced during fermentation were tested for antimicrobial properties. GBT30 and GBT37 isolates were selected based on their superior performance in probiotic property assays for further analysis. Molecular identification revealed these isolates as Pichia occidentalis (GBT30) and Pichia kudriavzevii (GBT37). Both strains demonstrated in vitro survivability under simulated gastrointestinal conditions and exhibited antimicrobial activity. Whole-genome sequencing of P. kudriavzevii GBT37 identified a genome size of 10,906,850 base pairs, distributed across four chromosomes with a GC content of 38.26%. Notably, secondary metabolite biosynthesis genes were located on contig 7. In addition, 26 probiotic-related genes, including GSY1, HSC82, HSP104, TPS1, ARN1, FLO1, ALA1, SIR2, and others, were identified in P. kudriavzevii GBT37, indicating its potential as a probiotic yeast. The traditional fermentation process of dadih offers probiotic yeasts with promising health benefits, supporting its potential as a functional food.
ANALYSIS OF MARRIAGE REGISTRATION IN GAMPONG ASAM PEUTEK WITHOUT PRECEDING RAFA' FROM A JURIDICAL PERSPECTIVE Nur Asiyah; Fatimah
Jurnal Hukum Samudra Keadilan Vol 19 No 2 (2024): Jurnal Hukum Samudra Keadilan
Publisher : Fakultas Hukum, Universitas Samudra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jhsk.v19i2.10652

Abstract

Marriage registration is the administrative data collection on marriages handled by marriage registrar officers with the aim of creating legal order. This research shows that regulations regarding examining marriage documents are regulated in Minister of Religion Regulation Number 19 of 2018 concerning Marriage Registration. Because checking documents is one of the processes of registering a marriage. However, the examination of this document is administrative in nature, so it does not determine whether a marriage is valid or not. The type of research carried out by the author is field research using qualitative methods, while the data collection techniques used are observation, interviews, and documentation. The analysis used is an inductive method, namely by presenting specific empirical facts from the research results and then ending with general conclusions. From this research it can be concluded that marriage registration was not carried out in accordance with existing laws and regulations. However, this is not a benchmark for whether a marriage is valid or not because document checks are administrative in nature. It's just that in the case of marriage registration, the documents were not checked, which is one of the stages of marriage registration. Examination of marriage documents, commonly called rafak, aims to ensure the suitability of the data of the prospective bride and groom and also that there are no obstacles to carrying out the marriage.
Investigation of catechin’s anti-inflammatory activity: A bioinformatics and molecular docking study Suprahman, Nisa Yulianti; Sari, Bulan Rosita; Fauziyya, Riri; Fatimah
Acta Biochimica Indonesiana Vol. 7 No. 2 (2024): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.199

Abstract

Background: Inflammation plays a key role in the progression of many chronic diseases. As a country with rich biodiversity, Indonesia offers numerous phytochemicals with potential for drug development, including catechin, a natural compound with anti-inflammatory properties. Objective: This study aimed to identify potential anti-inflammatory targets of catechin and evaluate its inhibitory potency through molecular docking simulations. Methods: Data acquisition and refinement were conducted using the NCBI, STRING, and STITCH databases, with intersections identified through Venn diagrams. Molecular docking was performed using AutoDockTools 1.5.6, and interactions were visualized with BIOVIA Discovery Studio. Results: Bioinformatics analysis predicted that catechin inhibits three pro-inflammatory proteins: COX-2, HSP90, and IL-2. Catechin’s inhibitory potential was indicated by negative binding energies and interactions with amino acid residues critical for target protein activity. Among the targets, IL-2 exhibited the lowest binding energy with catechin (-5.12 kcal/mol), suggesting it as the primary anti-inflammatory target. However, catechin’s binding affinity was lower than that of the native ligand (-11.78 kcal/mol). Conclusion: IL-2 is predicted to be the primary target for catechin’s anti-inflammatory activity. Structural modifications of catechin are recommended to enhance its binding affinity and therapeutic potential.
Co-Authors A.R. Pratiwi Hasanuddin Abd Quddus Al Badani Abdillah Abdillah, Ahmad Rifa'i Abdul Gafar Olawale Fahm Abdul Munir Ade Nabilla Yushifa Rahma Adhi Kristianto Sugianli Affandi, Moch Afmi Apriliani Afriani Nur Agra Alfin Zulfa Agus Supriyanto Aguscik agustin, riska Ahmad Adiarsa, Hilda Emeraldo Ahmad Gani Ahmad Junaidi Ahmad, Nurmiati Ai Hertati, Ai Ai-Ainun Astuti, Devi Yulia Aini Nurul Aini, Nuriah Ainun Fadilah Nasution Ainy Mumtaazah, Syifaa Aisyah Siregar Akmaliyah, Rizna Al Fath, Muhammad Thoriq Alia, Rahmah Alifia Nur Aisyah Alifia Putri Salsabila Almando Geraldi Alya Meiana, Nurma Amani, Febriyanti Nur Ameilia Zuliyanti Siregar AMELIA SETYAWATI, AMELIA AMINAH Amri Amrullah, Yozar Firdaus Ana Mariatul Khiftiyah ANAFRIN YUGISTYOWATI Ananda Putri, Ananda Ananda, Khairum Mahda Syahri Ananto , Irfan Ananto, Irfan Andiny, Puti Andirwana Andriani, Diana Andriyani Anggraeni, Wulan Eka Septi Ani Apriani, Ani Anisah Ardiana Anjani, Ajeng Distya Anjelika, Fara Annisa Annisa Azzahra, Annisa APON ZAENAL MUSTOPA Apon Zaenal Mustopa Arbayah Arfianty Arga Wahyu Fitri Ansyah Arifin, Moh. Zaenal Arifki, Muhammad Primo Armanila Arsyad Arsyad Genda Artati Arya Widiatmaja As'ad As'ad, As'ad Asad Asad, Asad Asdinar Asfahani, Shulhuly Asmaradhani, Debrinna T Astirima As’ad Auryel arkan alifi Ayu Ariana Ayu Tri Wahyuni Ayu, Putri Chandra Az Zahra, Fiza Azhar, Anang Anas Azhima, Idzni Aznawie, Amirah A’yun, Nadzifatul Bachruddin, Muhammad Badrun Taman Bae, Eun Ji Bakhtiar Bambang Trisakti Betawi, Usman Boyla Nurbaity Brigita Nur Diyan Agustiana Budi Setiawan Budi Yanto, Budi Budi, Listiyono Bunga Nur Siammukaromah, Jamalika Cahyo, Gilang Ramadhan Dwi Chairmanudin, Akbar Brillian Chairunnisa, Sheila Chalista, Angel Ribka Chihombori, Tatenda Calvin Cut Khairunnisah Harahap Danang Onggo Wasito Darma Jaya, Jaka Darmawan Darmini Darmo, Kasmuddin Darna Darna Darna Darwis Darwis Margolang Dea Ananda Deka yana, Arlitha Dela Dwi Alawiyah Destiana Desyandri Desyandri Devani Dewi Aminasty Siregar Dewi Purnamawati Dini Nur Seha Djari, Janny Adriani Do, Hoang Dang Khoa Dwi ASTUTI DWI NINGSIH SUSILOWATI Dwiego Chasenda, Dimas Effendi, Sri Rahmadaniati Eka Setia Budi Eka Yusriansyah Ekawati, Nurlaili El Hida, Ramdania Elisabeth Y Metekohy Elisabeth Yansye Metekohy Elli Hidayati Elva Tiara Elvi Suryani Emilla Dwi Nurrahma Endah Fauziningrum, Endah Endah Kanti Pangestuti, Endah Kanti Endang Purwaningrum Ermayuningsih, Baiq Reny Erwan Setyanoor Erwina kartika Dewi Ezra Ariendy Widodo Faisal Farah Aisyah Nafidiastri Farida Mayar Fatimah Izhara Fauzi, Resti Fauziridwan, Meydy Fauziyya, Riri Febrionny, Princessa Nandita Febriyansah, Aan Fenti A Tupanwael Firmansyah Firmansyah Firmansyah, Firman Syah Fithriyyah Fitri FITRI RAHMAWATI Fitria Latifatul Husna Fitriani Fitriyani Fitriyani Syukri Friska Linia Sari Futri Gatot Murti Wibowo, Gatot Murti Gilva Illavi Gita Mashlachatun Nisa Gunawan Gunawan Santoso Guspul, Ahmad Gusti Hidayah Fitriyani3 Hafidloh Hakimatul Husniyah HAMIDAH Handayani, Erna Handoko, Daniel Hanisa Hanum, Irma Surayya Hardianti Hardyati, Anastasia Hariyani Hartaty Harun, Hernianti Hasany, Ahmad Hayat, Saeed Fayzul Herdiansyah, Dadang Heri Wansyah Laia Hermawan Nagar Rasyid, Hermawan Nagar Hernianti Harun Hidayat Hidayat, Randy Hidayatullah, Riski Hikma, Nurul Hikmah, Gina Nur Hukom, Evi Hudriyah Hurriyah, Nada Husniawati, Neli I Made Samudra iin wahyuni Ilham Ashari, Ilham Indah Wahyuni Indianik Aminah Indra Surya, Indra Intansari, Anggita Isty IQBAL KUSNANDARSYAH Irawan, Herman Irfansyah, Febri Dwi Irma Shinta Dewi Irma Yulismawati Eka Masyitoh Irvan Isabella Hasiana, Isabella ISKANDAR Islawati Ismi Asmita Iswadi Ishak Alwi Iwan Jendri Mamangkey Johannes Siregar Juharis Jumai Latte Junairiah Junairiah Junairiah Kadim, Lina Arliana Nur Kadir, Adriani Kamal, Muhammad Badrul Kanukung, Nova Anugrah Kartika KARTIKASARI, NOVIA Khaerany Nisfiary, Reny Khairul Khairul Anshar Khairul Sabri KHOFIFAH KHOLIFAH Kismullah habib Kusumaratni, Dyah Ayu Ladewi, Yuhanis Leni Zahara Leny Latifah Lestari, Cicik Sri Lestari, Ema Lestari, Mutiara Levitasari Lia Dian Ayuningrum Liananiar Lillah , Mutia Lira, Rahmat Adnan Lisna Khairani Nasution Lomri, Muhamad M Tafsin M. Choiroel Anwar M. Iqbal Asnawi M. Taufiq M.Bahri Arifin Mandjarreki, Sakarudin Manguntungi, Baso Marisa Saputri Marnita Marsyom, Insren Loisa Martaleni - Maryam Latifah Harahap Maryam Latifah Harahap Masyitoh Maulana, Muhamad Arbhi Maulidi, M Nizar Meisaroh Mesran, Mesran Metekohy, Elisabeth Y Meutia, Sri MIFTAHUL JANNAH Mila Mirfa, Enny Mo, Yang Geun Mochammad Hatta Morti, Mohamad Farid Adam Bin Muh Amin , Astuti Muh. Yamin, Muh. Muhamad Syamsul Ma’arif Muhammad Muhammad Arya Adyva Muhammad Basri Muhammad Fiqih Ubaidi Muhammad Hafis Maulana Muhammad Jalaludin Assayuti Muhammad Rikzam Kamal Muhtadi M, Ridan Muis, Arman Multazam Munip, Al Muriyati Muslimah, Tiara Mustafa Musthofa, Imron Mustopa Mutiara, Ilma Muzhaffar, Muhammad Isfan Nabilatun Nisa’ Nadia Idris Nadiya Naelati Tubastuvi Nasution, Muhammad Iqbal Hanafi nasywa Nataly, Febryansyah Nathania, Gracella Ni'matuzahroh Niar Niken Agustin Nirmalasari, Ridha Nirmawan Nirmawan Nisa Yulianti Suprahman Ni’matuzahroh Noor Azmi Nabila Noor Hujjatusnaini Noor Yunida Triana Nordiansyah, Muhammad Norlena Nova Shella Rida Az-zahra Novi Shintia, Novi Novriyenni Nugroho, Febri Ardi Nur Anis Nabila Binti Suhaimi Nur Asiyah Nur Asiyah Nur Hadi Nur Winda Amalia Nuraeni, Yenny nurasyfa Nurfika Asmaningrum Nurhilaliyah Nurlaili Ekawati NURUL HIDAYAH Nurul Mubin Nurul Mutmainnah, Nurul Nurwani Nurwijayanti Nuryati Nuryati Octaviannus, Stephen Paramitha Tedja Trisnaning Pradhana, Annisa Laura Prasetya Lestari Prasetyo, Eko Yudha Pratama Tarigan, Budi Pratama, Ardian Pratama, Eric Endy Prima Selvia Megawati PUJI LESTARI Purnamasari, Yuli Purwaningtyas, Franindya Puspa, Esti a Puteri Maharani, Septia Puteri, Ananda Puteri, Azelia Putra, Gading Gunawan Putri Rahmi Putri, Indira Ari Rahayu Rahayuningtras, Nazil Dwi Rahma, Putri Rahma, Rahma Rahmadaniati Effendi, Sri Rahmah, Nisa Aulia Rahmat Adnan Lira Rahmat Aryandi Rahmawati, Hanif Nur raja Ramadhan , Alfikri Raoda rasmauli Refli, Redoyan Respati, Dwi Kismayanti Reza Fikri Maulana Reza Nuur Wahyuningtias Ridara, Rina Ridhwan Rifki Sakinah Nompo Rifqiyah Nur Umami, Rifqiyah Nur Rika Indri Astuti Rinanda sri rezeki Rini Fitriani Ririn Indriani Risda Amini rismanda Rizal, Yani Rizka Diah Fitri Rizkina, Seila Rizky Danang Susetyo Rizky Eka Putri, Rizky Eka Rizqiy, Raliya Rofiq Hidayat Roza Adila, Dian Ruly Rusmin Saragih, Rusmin RUSMIYATI Sadida, Qaulan Safarati, Nanda Safuridar Saifudin Saiful Bahri Saladin Ghalib SALAMUN Salamy, Muhammad Fath Alhaqqi Sanis Salnus, Subakir Salsabila, Syarifah salsabila, Syarifah salsabila Samputra, Palupi Lindiasari Samsudin Sapto Andriyono Sari Sari, Bulan Rosita Sariana Damis Satria Riki Mustafa Sekani Niriyah Septiani Selly Susanti Serang, Krisogonus Ephrino Setyadji, Veronika Setyanoor, Erwan Shalihah Shiva Nabilah Sholichah, Fatmawati Sholihah, Mar'atus Sholikah Siahaan, Hasnah Sidabutar, Rivaldi Silvia Kurnia Sari Silviana, Ilma Simorangkir, Eflin Novalynda Sinaga, Mersi Suriani Siradjuddin Sirait, Fadly Wafi SIREGAR, RAHMAH JULIANI Sithaningtyas Siti Haniyah Siti Hardianti, Siti Siti Harizah Siti Kholijah Siti Masfuah Siti Maysarah Sjamsir, Hasbi Sodikin Sofijan Hadi Sofith, Charissa Dini Sonny T. Lisal Sri Puji Astuti Wahyuningsih, Sri Puji Astuti Sri Sumarsih Sri Wahyuni Sri Zulaihati, Sri Stephanie Angel King Suci Hidayah Sagala Sudarmin, Nurfaisan Sudiyono SUGIYANTO Sukiati Sukiati Sugiono Sulaiman Ahmad Manurung Sulistiawati Suparlan . Suparman Supasman Emu Suryadi, Awel Suryani, Elvi Sustinah Limarjani Suyana, Nana Syahrul Rauf Syainda Dewi Syifa Pohan Syam, Zanni Latifah Syela Mutiara Zahra Syifa Syifa Ghaisani Sylvia Rozza Tamalia, Aqilla Kalyca Tantia Azzahra Tanwirullaily Telaumbanua, Faozatulo Tini Surtiningsih Titis Linangsari Toha Muhaimin Toyiburahman Tri Nurhariyati Tri Nurhariyati Tri Puji Priyatno Tria Astika Trini Suryani Kadir Trinugroho, Joko P Tulus Tumangger, Nurawalina Tunliu, Sarlina K Ulfa Safira Soliha Ulinnuha Ulviani, Maria Umairah, Hidayah Ummul Khair Untari Utami, Dinarossi Utaminingsih, Rizka Vandria Alamsyah Vidiana Anggeranika Wahyu Wardhana, Muhammad Wardha Jalil Warlinda Wati Fajzrina, Lati Nurliana Wilma Prafitri Winarti Wiratama, Adi Wiwik Handayani Y. Metekohy, Elisabeth Y.M, Elisabeth Yadi Arodhiskara, Yadi Yadi Suryadi Yanti Fitria Yenni Nuraeni Yeti Kartikasari, Yeti Yetty Yetty Yetty Yoga Tri Wijayanti Yolanda Yoneta Wamea Yulistyarani, Tri Yunita, Trisna Putri Yusuf Adi Pratama Zahrina Zebua, Dedy Zulkarnain, Abi Hasna Zuraifa