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PERILAKU DIET BERDASARKAN PENGETAHUAN TENTANG INDEKS GLIKEMIK PADA PASIEN DIABETES MELITUS PESERTA SEKOLAH PROLANIS BANGUNJIWO BANTUL Hidayati, Titiek; Suryani, Lilis; Akrom, Akrom
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol. 29 No. 4 (2023): OKTOBER-DESEMBER
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkm.v29i4.50611

Abstract

Cases of non-communicable diseases such as diabetes are often experienced by people with old age. Even in the Bantul region, this disease is included in the 10 groups of diseases that many people suffer. There needs to be independence from the community so that they do not depend on health service facilities such as the nearest health center. There are health cadres, providing education, carrying out actions with sticky media games, and closing with a temporary blood sugar level check. The method used to test the results of the service that has been carried out is by pre-test and post-test. Based on the test results, there is a significant relationship between knowledge and attitude variables. This can be because respondents who have been exposed to information regarding the glycemic index of food have a positive attitude towards choosing low-glycemic foods. Although there is no good relationship between attitude and behavior. In addition, there was an increase in the number of respondents who answered correctly on the pre-test and post-test on the pre-knowledge variable from 81 people to 96 people, the attitude variable from 85 people to 95 people, and the behavior variable from 80 people to 90 people. In addition, examination of blood sugar levels while on the chart shows that 38% are in the pre-diabetic category and 62% have normal blood sugar levels. The conclusion is that there is a positive increase between knowledge and attitudes after being given interventions in the form of education and checking blood sugar levels.
Validity and Reliability Test New Questionnaire of Knowledge, Perception, Family Support, and Adherence of Pregnant Women with Anemia Using TTD Supplement Atmadani, Rizka Novia; Arum, Dinar Famora; Akrom, Akrom; Urbayatun, Siti
Jurnal Kebidanan Midwiferia Vol. 11 No. 2 (2025): Oktober
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/midwiferia.v11i2.1720

Abstract

Anemia according to WHO (World Health Organization) is defined as crucial incidence during pregnancy. In adult groups, it is common in women of reproductive age, especially in pregnant women due to iron deficiency. Pregnant women need to consume Iron Folic Acid Supplement/Tablet Tambah Darah (TTD) regularly to prevent and overcome anemia. Several factors are important to be studied in anemic pregnant women. Therefore, researchers wanted to examine the validity and reliability of the new questionnaire. The purpose of this study was to determine the validity and reliability of the questionnaire on the level of knowledge, perceived barriers, perceived benefits, and adherence in anemic pregnant women in the use of TTD. This study uses quantitative research in the form of descriptive research and uses a cross-sectional design. Using non- probability sampling with purposive sampling technique and 100 mothers. In research conducted in September 2023 showed that the validity and reliability test questionnaire on the questionnaire level of knowledge, perceived barriers, perceived benefits, family support and adherence questions are valid and also reliable with Cronbach alpha above 0.6.
Gambaran Kejadian Efek Samping Kemoterapi Pasien Kanker Payudara Yang Menggunakan M-Health App “Pantau Kanker” Di Rumah Sakit Kota Yogyakarta Nur P, Kanindya; Zukhruf Saputri, Ginanjar; Supadmi, Woro; Akrom, Akrom; Muhlis, Muh
JURNAL FARMASI GALENIKA Vol 11 No 3 (2024): Jurnal Farmasi Galenika Vol 11 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i3.345

Abstract

Breast cancer is a type of cancer with a fairly high death rate. DIY Province has the highest prevalence of breast cancer in Indonesia. One of the medical ways to treat cancer is chemotherapy which uses cytostatic drugs, aimed at killing or slowing the growth of cancer cells. However, these drugs cause side effects in patients. Education is needed in dealing with side effects in order to monitor the patient's condition. Therefore, this research was conducted to determine the incidence of side effects of chemotherapy in breast cancer patients who use the M-Health app "Pantau Kanker" at Yogyakarta General Hospital. The research method used descriptive observational, with 41 patients as respondents. Recruitment was carried out using informed consent based on inclusion and exclusion criteria. Data collection was carried out using CRF (case report form) monitoring drug side effects. Data collection was carried out on the first, third and fifth days after chemotherapy. Monitoring is carried out through direct interviews with patients and through searching medical record data. Monitoring for nausea, vomiting and pain is carried out using the "Pantau Kanker" application based on the M-Health app with the VAS (visual analogue scale).  The results of this study showed that nausea often occurs on the first day, due to immediate side effects (24 hour duration). Then, those including delayed ADRs such as anorexia, insomnia are often found on the third day, while on the fifth day the majority occur alopecia and tingling pain. Some side effects, such as diarrhea, constipation, stomatitis (mouth ulcers), and fever, are not experienced by many patients. Some side effects, such as diarrhea, constipation, stomatitis (mouth ulcers), and fever are not experienced by many patients. The therapy regimen used is dominated by low emetogenic, so that the majority of side effects that appear are in the mild category and do not interfere with the patient's activities. The conclusion of the study shows that monitoring of side effects when using cytostatic drugs occurs between days 1 to 5, the majority are in the mild category so that the patient's daily activities can still run well.
The Perception, Religiosity, Adherence, and Quality of Life of Diabetes Mellitus Patients in Primary Health Center: Persepsi, Religiusitas, kepatuhan dan Kualitas Hidup Pasien Diabetes Mellitus Di Fasilitas Kesehatan Primer Aristia, Bella Fevi; Akrom; Saputri, Ginandjar Zukhruf; Mustofa
Jurnal Ilmiah Farmasi Vol. 20 No. 1 (2024): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol20.iss1.art10

Abstract

Background: Diabetes mellitus is a chronic disease that can overcome complications and decrease quality of life.Objective: The purpose of this study was to determine the effect of counseling religious nuance and pill box on perception, religiosity, quality of life, and adherence in DM patients who get oral antidiabetic in the outpatient of Jetis 1 Primary Health Center, Bantul Regency.Method: This type of research is quasi-experimental, utilizing a pretest and posttest design with a control group. Recruitment of subjects was done by purposive sampling based on exclusion and inclusion criteria with a simple randomization of allocations in order to obtain a sample of 71 people, divided into control (n = 36) and treatment (n = 35) groups. The instrument to assess the success of counseling is the perception questionnaire (B-IPQ), religiosity, and quality of life (EQ5D-3L) that has been validated, while to measure compliance, it is calculated using the pill count method. Statistical analysis using chi square, t test, independent t-test, Wilcoxon test, and Mann-Whitney test with 95% confidence level.Results: The results showed that the treatment group after being given counseling and pill boxes had a better perception (31.37±6.44) than the control group (34.47±7.16) (p<0,05). The treatment group religiosity score was higher (64.28±3.44) compared to the control group (62.17±4.64) (p<0.05). The adherence value of treatment group (96.28±10.32) is greater than that of the control group (88.37±12.39), p<0.05. The majority of patients are still able to walk, perform self-care independently, and carry out daily activities. The highest mean quality of life score was in the treatment group (0.95±0,08) with a mean VAS (77.40±6.31).Conclusion: Based on the results of this study, it can be concluded that there is an influence of giving counseling religious nuance and pill box, which is marked by an increase in perception, religiosity, quality of life, and adherence.Keywords: Diabetes mellitus, perception, religiosity, adherence, quality of life
Black Cumin Seeds Extract Increase Lymphocyte Activity in IFN-γ Secretion in Sprague Dawley Rat (SD) Induced by Dimethylbenzantracene Akrom, Akrom; Hidayati, Titiek; Sagiran, Sagiran; Indrayanti, Indrayanti
Indonesian Journal of Cancer Chemoprevention Vol 10, No 3 (2019)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev10iss3pp140-148

Abstract

Interferon-gamma (IFN-γ) is one of the central cytokines in the anti-carcinogenesis immune response. Black cumin seeds (BCS) have an active content of thymoquinone and unsaturated fatty acids with biological activity as immunomodulators. This study aimed to determine the effect of administration of BCS extract on IFN-γ secretion activity by DMBA-induced SD rat lymphocytes. In vivo experimental study on DMBA-induced SD rats, BCS extract was given with three doses for two weeks before being induced and five weeks during DMBA induction. IFN-γ levels in lymphocyte culture supernatants were determined by the ELISA method. The difference in IFN-γ levels between groups was analyzed by ANOVA test, the significance of 95%. The results showed that administration of BCS extract for 14 days did not affect cellular composition toward the edge of the test animal. BCS extract can increase IFN-γ secretion activity by DMBA-induced SD rat lymphocytes.Keywords: black cumin seed, IFN-γ; DMBA: immunomodulator, carcinogenesis.
Antioxidant Potential of the Asteraceae Family in Counteracting Free Radicals in Cigarette Smoke: An Overview Azali, Aulia Syafadilla; Rajab, Muhammad Andy; Lathifah, Sofiani; Akrom
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/4vbm3x10

Abstract

Cigarette smoke exposure triggers oxidative stress in the respiratory system through an increase in free radicals and a decrease in endogenous antioxidant activity, which contributes to lung damage and chronic diseases such as COPD and lung cancer. This study aims to investigate the potential of species from the Asteraceae family as a source of natural antioxidants in protecting the lungs and trachea from damage caused by exposure to free radicals in cigarette smoke. The method used is a Systematic Literature Review (SLR) with reference to the PRISMA 2020 guidelines. Literature searches were conducted systematically through the PubMed, ScienceDirect, and Google Scholar databases until June 2025. The inclusion criteria included in vivo studies using Asteraceae plant extracts in animals with induced oxidative stress in the respiratory system, as well as involving the measurement of biomarkers such as MDA, GSH, SOD, and CAT. Of the 198 articles found, 10 articles met the criteria and included species such as Tridax procumbens, Chromolaena odorata, Pulicaria petiolaris, and Baccharis retusa. The results showed that these species had significant antioxidant activity through their flavonoid, polyphenol, and triterpenoid compound content. However, most studies did not use a direct cigarette smoke exposure model. In conclusion, the Asteraceae family has great potential as a source of natural antioxidants to protect the respiratory system from oxidative stress, although further research with more relevant exposure models is needed. Toxicology and metabolomics approaches are also needed to strengthen the evidence for practical application in the treatment of lung diseases caused by cigarette smoke.
Pengembangan Media Scrapbook Berbasis Budaya Lokal untuk Meningkatkan Hasil Belajar IPAS pada Materi Keragaman Budaya Kinanti, Putri; Akrom, Akrom; Meiliawati, Fithri
Awwaliyah: Jurnal Pendidikan Guru Madrasah Ibtidaiyah Vol. 7 No. 1 (2024): Awwaliyah: Jurnal PGMI
Publisher : Program Studi Pendidikan Guru Madrasah Ibtidaiyah (PGMI) Fakultas Tarbiyah dan Ilmu Keguruan (FTIK) Institut Agama Islam Tarbiyatut Tholabah (IAI TABAH) Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58518/awwaliyah.v7i1.2566

Abstract

The aim of this research is to develop local culture-based scrapbook media on cultural diversity material and to find out whether this media is feasible and can improve student learning outcomes. The method used in the research is R&D (Research and Development) with Thiagarajan's 4D model, which has four stages: define, design, develop, and disseminate. Data collection techniques used were observation, interviews, questionnaires, pre-test and post-test sheets. The product was tested in class IV with 18 students. Based on the research results, local culture-based scrapbook media has an average validation value from the three experts, namely 92% in the "Very Appropriate" category. The increase in student learning outcomes after using learning media shows the effectiveness of the media by obtaining an N-Gain value of 0.76 in the "High" category and an N-Gain percentage of 76.39% in the "Effective" category. Therefore, the use of local culture-based scrapbook media can improve student learning outcomes and is very suitable for use as a learning medium.
Hepatoprotective effect of chewable tablet of Centella asiatica (L.) Urb extractin Wistar rats induced by high fat diets Akrom; Feri Anggita Hastanto; Nurani, Laela hayu
Indonesian Journal of Pharmacology and Therapy Vol 2 No 1 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1128

Abstract

Gotukola or Centella asiatica (L.) Urban contains high flavonoids which well known as fatty liver protector. This study aimed to evaluate the hepatoprotective effect of chewable tablet of C. asiatica (L.) Urb extract (CTCE) in Wistar rats induced by high fat diets. Twenty-one Wistar male rats aged 8-12 weeks with body weight ranging from 100-150 g were used in this study. Rats were randomly divided into seven groups i.e. Group 1 as normal control, rats were given standard food, Group 2 as high fat diets control, rats were induced high fat diets (HFD),Group 3 as positive control, rats were induced HFD and given simvastatin, Group 4 as placebo control, rats were induced HFD and given placebo, Group 5-7 as treatment group, rats were induced HFD and given CTCE at doses of 100, 200 and 300 mg/kg BW, respectively. The HFD induction was conducted for five weeks andthe CTCE was given for one week in the last week of the induction. At the end of the intervention, blood triglyceride levels and SGPT as well SGOT activities were examined. Analysis of variance (ANOVA) with confidence interval of 95% (p<0.05) was applied. The results showed that the HFD induction increased the serum triglyceride levels and SGPT activity. The serum triglyceride levels and SGPT activity of Group 2 were significantly higher than Group 1 (p<0.05). Furthermore, the simvastatin and CTCE administration reduced the serum triglyceride levels and SGPT activity. The serum triglyceride levels and SGPT activity of Group 3, 5, 6and 7 were significantly lower than Group 2 and 4 (p<0.05). In addition, the serum triglyceride levels and SGPT activity of Group 5, 6 and 7 were significantly lower than Group 3 (p<0.05). In conclusion, CTCE can reduce the serum triglyceride levels and SGPT activity in Wistar rats induced by HFD.
Implementation of a Web-Based Student Candidate Selection System Using the Simple Additive Weighting Algorithm Akrom
Jurnal Inotera Vol. 10 No. 2 (2025): July - December 2025
Publisher : LPPM Politeknik Aceh Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31572/inotera.Vol10.Iss2.2025.ID538

Abstract

The rapid development of information technology in the era of globalization encourages various sectors to adopt digital technology, including in the field of education. One important aspect that requires the optimization of technology is the selection process for new student candidates. The manual selection method often takes a lot of time, is prone to errors, and lacks transparency and objectivity. Therefore, the implementation of an information technology-based selection system becomes a relevant and urgent solution. This research aims to design and implement a website-based selection system for student candidates using the Simple Additive Weighting (SAW) algorithm at XYZ Junior High School.The SAW algorithm is chosen for its ability to solve multi-criteria decision-making problems in a simple, efficient, and effective manner. This system is designed to process data of prospective students based on a number of predetermined criteria and then calculate the final scores to determine the rankings of prospective students objectively. The system development process includes stages of needs analysis, interface and system design, program implementation, and evaluation of system functionality and performance. The results of the implementation show that this system can accelerate the selection process, improve calculation accuracy, and provide transparency and fairness in decision-making. Additionally, this system can also serve as a reference for other schools that want to adopt similar technology to enhance the efficiency and quality of the new student selection administration process.
The Effectiveness of Herbal Supplements on Improving the Anthropometric Status of Stunted Children Hardia, Lukman; Akrom, Akrom; Sulistyani, Nanik
Jurnal Kesehatan Manarang Vol 11 No 3 (2025): December 2025
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v11i3.1597

Abstract

Stunting has become a health issue that threatens the future generation of Indonesia, which is why the government has set a target prevalence of stunting at 14% by 2024. This has become a challenge because some areas, such as Sorong Regency, still have a higher prevalence of stunting compared to the national prevalence. One of the causes of stunting is malnutrition, so efforts are needed to address this issue by utilizing Indonesia's natural wealth, such as herbal honey, Curcuma xanthorrhiza, and black cumin, which are widely used by the community to tackle various health problems. The objective is to determine the effect of administering herbal honey made from temulawak and black cumin on changes in the anthropometric status of stunted children in Sorong Regency. This type of research is quantitative, using a quasi-experimental research design with a pre- and post-test with a control group design. The sampling technique used is purposive sampling, with a total sample of 60 children divided into 3 groups: the normal control group (20 children), the stunting control group (20 children), and the stunting intervention group (20 children). The data analysis techniques used in the research are paired-samples t-test and independent-samples t-test. The statistical test of the mean difference between the pre- and post-test between the intervention group and the control group showed a significant increase in body weight (average increase of 1.60 ± 0.66 kg, p < 0.001), height (1.49 ± 0.74 cm, p < 0.001), and z-score height-for-age (-0.42 ± 0.22 SD, p < 0.001). The administration of herbal honey, Curcuma xanthorrhiza, and black cumin can improve the anthropometric status of stunted children in Sorong Regency.
Co-Authors - Sagiran Aa Setiawan Abas, Siti Nur Rahmatiya Abdelghani Echchabi Abdul Aziz Abdul Fadlil Abdul Fat-Han Ismail Abdul Hamid Abdullah Ayedh abdurrahman rahman Ade Permatasari Adeliyanti Adeliyanti Adhy Kurnia Triatmaja Aditya Peramana Maheztra Adnan Adnan, Adnan Adrianison Adrianison Ae Suaesih Afif Alwanuddin Afifah Naziihah Afrizal Afrizal Agamasi, Amalia Agariadne Dwinggo Samala Agesti Hasna Ekawati Agita, Adinda Puspa Agnes Jatiningrum Agung Wibowo Agus Khobir Permana Agus Wibowo Agustina Susilowati Agustyana, Andini Ahmad Bahruddin Ahmad Hafidzul Kahfi Ahmad Naufal, Ahmad Ahmad Suryadi, Ahmad Ahmad Turmudzi Ahmad Turmudzi, Ahmad Ainun Muthoharoh Ainun Rahma Firdausy Aisyah Shofiyati Ajeng Dianing Kartika Aji, Dicky Qulyubi Akhmad Baihaqi Akmal Hakim Ali Akbar Ali Imron Alif Darmawan Alifah Fidela Allen Pranata Putra Alvenus Willim, Herick Amalia, Farah Amalia, Nur Rizky Amaliyah Tazkiyah Amandha Boy Timor Aminuyati Amir M. Suruwaky Amiruddin Saleh Anak Agung Ayu Sisthayoni Anak Agung Ngurah Yusa Darmadi Andang Adi Fitria Hananto Andi Baso Thabrani Andi Ifriani Harun Andi Ifriani Harun* Andi Pancanugraha Andi Widjaya Andrew John Macnab Andriana Wihartantri Kusumaningrum Andrijono Andrijono Andriyanto Andriyanto Anestia Retno Kusumastuti Anggun Pulihana Wilujeng Anggy Rima Putri Aniq Astofa Anisa Nurfitriana Anita Dwi Putri Galla Annisa Eka Fitrianti Antonius, Rosanio Anwar, Muslih Aprilia Divi Yustita Apriliana Vivy Candra Ardhia Fefrine Indarta Ardianik Ardianik Ardiyanto, Restu Arhandy Arfah Ari Nurweni Ari Pramitha Suandi Ari Simbara Ari Simbara, Ari Arief Rahman Ariestya Indah Permata Sari Arif Budi Setianto Arif Santoso Arifan Q. Raharjo Arihni Arihatal Jannah Aris Purwanto Aristia, Bella Fevi Ariyani, Herda Arman Syah Putra Arman Syah Putra Armansyah T Arri Handayani Arsi Arsi Arsip Perangin angin Arum, Dinar Famora Ary Norsaputra Arya Adiningrat Aryadillah, Entus Aryan Sugara Asti Reswari Dewi Astofa, Aniq Aulia Farah Diba Aulia Uswatun Khasanah Auliya Salsabilla Azali, Aulia Syafadilla Baehaqi Bagus Haryadi Bambang Nolo Kresno Barnabas Bonardo Hana Christina Bashor Fauzan Muthohirin Baso Mukramin Bastian Addy Sanjaya Bhisma Murti Billy Nugraha Bimo Eka Yudha Saputra Bisyri, Hanifah Bisyri, Hanifah Bowo Hery Prasetyo, Bowo Hery Brian Rinaldy Irsyad Budi Al Amin Budiyono Budiyono Budiyono Budiyono Burhannudin Ichsan Caesar Bagus Reyaldi Candra Agustina Canggih Puspo Wibowo Capritasari, Rafiastiana Chaerul Umam Wardani Chairul Amni, Chairul Christa A. M. 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