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Tinggi Ilmu Ekonomi Widya Wiwaha Program Magister Manajemen Kajian Bisnis STIE Widya Wiwaha Ibtida'i : Jurnal Kependidikan Dasar Jurnal Mantik CERATA Jurnal Ilmu Farmasi Journal of Islamic Accounting and Tax (JIATAX) Pharmacoscript Jurnal Kefarmasian AKFARINDO Journal of Applied Engineering and Technological Science (JAETS) Jurnal Serunai Matematika JPAP (Jurnal Praktisi Administrasi Pendidikan) Sutasoma : Jurnal Sastra Jawa Journal of Vocational Education Studies (JOVES) Jurnal Ilmiah Pendidikan Matematika Al Qalasadi Jurnal Educatio FKIP UNMA Pharma Xplore : Jurnal Sains dan Ilmu Farmasi JURNAL PEMBANGUNAN HUKUM INDONESIA Kontribusia : Research Dissemination for Community Development JOURNAL OF INFORMATION SYSTEM MANAGEMENT (JOISM) Jurnal Agroristek Jurnal Kesehatan Jurnal Manajemen Universitas Bung Hatta Jorpres (Jurnal Olahraga Prestasi) KONSEP DAN TUJUAN PADA TINJUAN BISNIS SYARIAH ILTEK : Jurnal Teknologi Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Jurnal Peduli Masyarakat Jurnal Riset Akuntansi dan Manajemen Malahayati (JRAMM) Longda Xiaokan : Journal of Mandarin Learning and Teaching JURNAL AKTUAL AKUNTANSI KEUANGAN BISNIS TERAPAN (AKUNBISNIS) Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Fokus Manajemen Bisnis Jupeko (Jurnal Pendidikan Ekonomi) SUPERMAT (JURNAL PENDIDIKAN MATEMATIKA) Nusantara Science and Technology Proceedings Jurnal REKSA: Rekayasa Keuangan, Syariah dan Audit Jurnal Penelitian ADDIN Akrab Juara : Jurnal Ilmu-ilmu Sosial Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat Promotor: Jurnal Mahasiswa Kesehatan Masyarakat Al-Bidayah: Jurnal Pendidikan Dasar Islam Journal of Industrial Engineering & Management Research (JIEMAR) Jurnal Mandala Pengabdian Masyarakat Jurnal Fakultas Ilmu Keislaman UNISA Kuningan Jurnal Dinamika Sosial Ekonomi IJISTECH Awwaliyah Serambi Journal of Agricultural Technology Jurnal Insan Farmasi Indonesia Jurnal Eksis Hydrogen: Jurnal Kependidikan Kimia Devotion: Journal of Research and Community Service Nusantara Hasana Journal INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Buana Farma DedikasiMU: Journal of Community Service Abditeknika - Jurnal Pengabdian Kepada Masyarakat Civil Engineering and Technology Journal International Journal of Social Service and Research JUSTIAN - Jurnal Sistem Informasi Akuntansi Journal of Economics and Business Letters Journal of Innovation in Community Empowerment (JICE) Simpatik: Jurnal sistem Informasi dan Informatika JIAPI: Jurnal Ilmu Administrasi dan Pemerintahan Indonesia PESAGI (Jurnal Pendidikan dan Penelitian Sejarah) PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Cermin Dunia Kedokteran Prosiding Konferensi Nasional PKM-CSR Jurnal Interkom : Jurnal Publikasi Ilmiah Bidang Teknologi Informasi dan Komunikasi Jurnal Visi Komunikasi International Journal of Science and Society (IJSOC) JES-MAT (Jurnal Edukasi dan Sains Matematika) CITIZEN: Jurnal Ilmiah Mulitidisiplin Indonesia Nusantara Journal of Behavioral and Social Science Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan International journal of education and learning Chemical Engineering Journal Storage (CEJS) Medical Sains : Jurnal Ilmiah Kefarmasian Labatila: Jurnal Ilmu Ekonomi Islam Jurnal Locus Penelitian dan Pengabdian Jurnal Ilmu Kebidanan (Journal of Midwivery Science) Jurnal Pusat Inovasi Masyarakat Jurnal Litbang Industri Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Jurnal Jarlit Jurnal Riset Akuntansi dan Bisnis Indonesia Jurnal Airaha JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JAMAIKA: Jurnal Abdi Masyarakat Jurnal Bakti Untuk Negeri Lambda: Jurnal Ilmiah Pendidikan MIPA dan Aplikasinya Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Tamkin: Jurnal Pengembangan Masyarakat Islam AMMA : Jurnal Pengabdian Masyarakat APPA : Jurnal Pengabdian Kepada Masyarakat Journal of Public Health and Pharmacy Journal of Food and Pharmaceutical Sciences Jurnal Farmasi Galenika Indonesian Journal of Pharmacology and Therapy
Akrom, Akrom
Universitas Ahmad Dahlan
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Hepatoprotective effect of chewable tablet of Centella asiatica (L.) Urb extractin Wistar rats induced by high fat diets Akrom; Feri Anggita Hastanto; Nurani, Laela hayu
Indonesian Journal of Pharmacology and Therapy Vol 2 No 1 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1128

Abstract

Gotukola or Centella asiatica (L.) Urban contains high flavonoids which well known as fatty liver protector. This study aimed to evaluate the hepatoprotective effect of chewable tablet of C. asiatica (L.) Urb extract (CTCE) in Wistar rats induced by high fat diets. Twenty-one Wistar male rats aged 8-12 weeks with body weight ranging from 100-150 g were used in this study. Rats were randomly divided into seven groups i.e. Group 1 as normal control, rats were given standard food, Group 2 as high fat diets control, rats were induced high fat diets (HFD),Group 3 as positive control, rats were induced HFD and given simvastatin, Group 4 as placebo control, rats were induced HFD and given placebo, Group 5-7 as treatment group, rats were induced HFD and given CTCE at doses of 100, 200 and 300 mg/kg BW, respectively. The HFD induction was conducted for five weeks andthe CTCE was given for one week in the last week of the induction. At the end of the intervention, blood triglyceride levels and SGPT as well SGOT activities were examined. Analysis of variance (ANOVA) with confidence interval of 95% (p<0.05) was applied. The results showed that the HFD induction increased the serum triglyceride levels and SGPT activity. The serum triglyceride levels and SGPT activity of Group 2 were significantly higher than Group 1 (p<0.05). Furthermore, the simvastatin and CTCE administration reduced the serum triglyceride levels and SGPT activity. The serum triglyceride levels and SGPT activity of Group 3, 5, 6and 7 were significantly lower than Group 2 and 4 (p<0.05). In addition, the serum triglyceride levels and SGPT activity of Group 5, 6 and 7 were significantly lower than Group 3 (p<0.05). In conclusion, CTCE can reduce the serum triglyceride levels and SGPT activity in Wistar rats induced by HFD.
Implementation of a Web-Based Student Candidate Selection System Using the Simple Additive Weighting Algorithm Akrom
Jurnal Inotera Vol. 10 No. 2 (2025): July - December 2025
Publisher : LPPM Politeknik Aceh Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31572/inotera.Vol10.Iss2.2025.ID538

Abstract

The rapid development of information technology in the era of globalization encourages various sectors to adopt digital technology, including in the field of education. One important aspect that requires the optimization of technology is the selection process for new student candidates. The manual selection method often takes a lot of time, is prone to errors, and lacks transparency and objectivity. Therefore, the implementation of an information technology-based selection system becomes a relevant and urgent solution. This research aims to design and implement a website-based selection system for student candidates using the Simple Additive Weighting (SAW) algorithm at XYZ Junior High School.The SAW algorithm is chosen for its ability to solve multi-criteria decision-making problems in a simple, efficient, and effective manner. This system is designed to process data of prospective students based on a number of predetermined criteria and then calculate the final scores to determine the rankings of prospective students objectively. The system development process includes stages of needs analysis, interface and system design, program implementation, and evaluation of system functionality and performance. The results of the implementation show that this system can accelerate the selection process, improve calculation accuracy, and provide transparency and fairness in decision-making. Additionally, this system can also serve as a reference for other schools that want to adopt similar technology to enhance the efficiency and quality of the new student selection administration process.
The Effectiveness of Herbal Supplements on Improving the Anthropometric Status of Stunted Children Hardia, Lukman; Akrom, Akrom; Sulistyani, Nanik
Jurnal Kesehatan Manarang Vol 11 No 3 (2025): December 2025
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v11i3.1597

Abstract

Stunting has become a health issue that threatens the future generation of Indonesia, which is why the government has set a target prevalence of stunting at 14% by 2024. This has become a challenge because some areas, such as Sorong Regency, still have a higher prevalence of stunting compared to the national prevalence. One of the causes of stunting is malnutrition, so efforts are needed to address this issue by utilizing Indonesia's natural wealth, such as herbal honey, Curcuma xanthorrhiza, and black cumin, which are widely used by the community to tackle various health problems. The objective is to determine the effect of administering herbal honey made from temulawak and black cumin on changes in the anthropometric status of stunted children in Sorong Regency. This type of research is quantitative, using a quasi-experimental research design with a pre- and post-test with a control group design. The sampling technique used is purposive sampling, with a total sample of 60 children divided into 3 groups: the normal control group (20 children), the stunting control group (20 children), and the stunting intervention group (20 children). The data analysis techniques used in the research are paired-samples t-test and independent-samples t-test. The statistical test of the mean difference between the pre- and post-test between the intervention group and the control group showed a significant increase in body weight (average increase of 1.60 ± 0.66 kg, p < 0.001), height (1.49 ± 0.74 cm, p < 0.001), and z-score height-for-age (-0.42 ± 0.22 SD, p < 0.001). The administration of herbal honey, Curcuma xanthorrhiza, and black cumin can improve the anthropometric status of stunted children in Sorong Regency.
PELATIHAN PEMBUATAN SABUN CUCI ANTIBAKTERI BERBASIS HERBAL DAUN TEH HIJAU PADA SISWA DAN GURU SEKOLAH INDONESIA DAVAO. DAVAO CITY, PHILIPINA Utami, Dwi; Akrom, Akrom; Pertiwi , Deasy Vanda; Nafiah, Mufidatun; Hartati, Meity; Antonius, Rosanio; Ardiyanto, Restu; Suryo Putro, Nur Fitriansyah
Jurnal Bakti untuk Negeri Vol 5 No 02 (2025): Jurnal Bakti Untuk Negeri
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/cv9jkf41

Abstract

Tea leaves and betel leaves are among the abundant local resources in the Davao region, Davao City, Philippines, that have not been optimally utilized. This community service aims to improve the knowledge and skills of students at the Indonesian School in Davao in making herbal dish soap from tea leaves. This activity was conducted using a training and hands-on practice method for 45 students and teachers. Training material on the benefits of tea leaves as a natural ingredient in dish soap and how to make it. The results of the service show an increase in knowledge, from 30% before training to 68.57%. A total of 85% of participants were able to make green tea dish soap after attending the training, compared to 45% previously. Students were able to understand the process of making herbal dish soap from tea leaves and apply it in their daily lives. This community service can make a positive contribution to society and the surrounding environment. This activity is also an example of integrating knowledge and skills about creating natural and environmentally friendly products into the school curriculum.
Hubungan Religiusitas dengan Kepatuhan Pasien Diabetes Melitus Rawat Jalan di Puskesmas Jetis 1 Bantul Aristia, Bella Fevi; Akrom, Akrom
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 6 No. 1 (2022)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v6i1.2023

Abstract

Diabetes mellitus (DM) merupakan penyakit jangka panjang yang mempengaruhi fisik dan psikologis penderitanya. Religiusitas yang dimiliki seseorang dapat berpengaruh pada usaha seseorang untuk sembuh dari penyakitnya, karena ada kesadaran jika penyakit merupakan ujian yang diberikan oleh Tuhan sehingga sebagai manusia berkewajiban untuk menjalani ikhtiar pengobatan. Tujuan penelitian untuk menilai hubungan antara religiusitas dengan kepatuhan pengobatan pada pasien diabetes melitus rawat jalan di Puskesmas Jetis 1 Bantul. Penelitian dilakukan pada bulan Desember 2018 – Maret 2019. Metode yang digunakan dalam penelitian ini adalah cross sectional dengan mengambil 71 pasien diabetes melitus yang memenuhi kriteria inklusi dan dipilih melalui pengambilan sampel secara acak. Proses pengumpulan data menggunakan instrumen demografi, kuesioner religiusitas dan pill box untuk melihat kepatuhan pengobatan dihitung dengan metode pillcount. Analisis data dilakukan secara kualitatif dan kuantitatif. Nilai korelasi dianalisis menggunakan korelasi spearman. Rata-rata usia penderita DM 59,52±8,74 tahun, jenis kelamin perempuan sebanyak 64,79%, rata-rata lama menderita DM 7,21± 4,95 tahun. Sebesar 71,83% pasien patuh mengkonsumsi obat. Terdapat hubungan yang positif signifikan antara religiusitas dan kepatuhan dengan nilai r=0,392 dan p=0,001. Religiusitas yang dimiliki oleh pasien secara bermakna berhubungan dengan kepatuhan pengobatan, semakin tinggi religiusitas maka semakin tinggi kepatuhan pengobatan. 
Pengaruh Pemberian Konseling Singkat Farmasi dan Penggunaan Pill Box terhadap Pengetahuan dan Kepatuhan Minum Obat Pasien Diabetes Melitus di Puskesmas Jetis 1 Bantul Wulandari, Shinta; Akrom, Akrom
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 6 No. 1 (2022)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v6i1.2280

Abstract

Diabetes melitus merupakan penyakit metabolis yang kronis dan menjadi salah satu penyebab kematian terbesar di dunia. Angka prevalensi diabetes melitus yang tinggi di D.I Yogyakarta menjadi alasan mengapa pasien dengan diabetes melitus perlu mendapatkan perhatian lebih. Penelitian ini berlangsung pada periode Desember 2018 – Maret 2019 dan memiliki tujuan untuk mengetahui tingkat pengetahuan dan kepatuhan pasien dalam minum obat setelah diberikan konseling. Penelitian ini memiliki desain quasi ekperimental dengan rancangan yang digunakan adalah randomized pretest – post-test control group design. Pengambilan data secara prospektif dan dilakukan dengan wawancara tatap muka. Analisis pada penelitian ini menggunakan SPSS dengan menggunakan Uji Mann Whitney, Uji Wilcoxon dan Uji dependent sampel. Hasil dari penelitian ini yaitu terdapat perbedaan tingkat pengetahuan yang signifikan (nilai p: 0,000) pada kelompok perlakuan dibandingkan dengan kelompok kontrol. Kepatuhan pasien juga mengalami perbedaan yang signifikan (nilai p: 0,041) pada kelompok perlakuan dibandingan dengan kelompok kontrol. Perlakuan yang diberikan adalah pemberian konseling singkat farmasi oleh apoteker dan pemberian pill box untuk meingkatkan kepatuhan pasien dalam minum obat.
In vitro evaluation of antioxidant properties of Moringa oleifera, Centella asiatica, and Nigella sativa: individual and combined effects Capritasari, Rafiastiana; Setianto, Arif Budi; Akrom; Rais, Ichwan Ridwan; Anwar, Muslih; Sun, Suny
Pharmaciana Vol. 15 No. 3 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i3.30597

Abstract

Oxidative stress, a condition linked to various degenerative diseases, occurs when reactive species build up in the body. These harmful molecules often come by environmental factors like air pollution as well as by unhealthy lifestyle habits. Fortunately, nature gives a defense system: plants produce flavonoids and other phenolic substances that act as natural antioxidants, handling to neutralize reactive species and protecting the body by their damaging effects. The objective of the study was to determine the phytochemical content of extracts of M. oleifera leaf, C. asiatica leaf, and N. sativa Oil and their operation as antioxidants. The study applied both qualitative and quantitative phytochemical tests to measure flavonoid levels in the extracts. Bioactive substances were then identified through GC-MS and LC-HRMS, while antioxidant operation was assessed utilizing the DPPH method. The outcomes were drawn that Moringa oleifera and Centella asiatica extracts contained flavonoids, alkaloids, tannins, saponins, and steroids, while Nigella sativa oil contained terpenoids. Among the three, LC-HRMS screening drawn that Moringa oleifera extract had the highest diversity of flavonoid substances. The outcomes of GC-MS obtained 13 components identified in Nigella sativa oil, one of that was thymoquinone. The antioxidant operation IC50 scores were as follows: 57.943 ± 3.481 µg/mL (M. oleifera), 66.578 ± 1.979 µg/mL (C. asiatica), 56.174 ± 1.604 µg/mL (N. sativa), and 51.128 ± 1.724 µg/mL (polyherbal combination). All the samples demonstrated strong antioxidant operation, and notably, the combination of extracts proved to be more effective than when each to be utilized individually.
Flavonoid synergy in antioxidant optimization: a study of Apium graveolens and Orthosipon stamineus Astuti, Febriana; Akrom; Setianto, Arif Budi; Hidayati, Titiek; Mustofa; Anwar, Muslih; Sun, Suny
Pharmaciana Vol. 15 No. 3 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i3.30599

Abstract

Oxidative stress, which arises by an imbalance among the formation of free radicals and the body's antioxidant defenses, is a pivotal factor in the pathogenesis of numerous degenerative abnormalities, comprising cardiovascular abnormality. Flavonoids, that are natural chemicals by antioxidant capabilities, have been identified as potential agents for protection against the adverse impacts of oxidative stress. The objective of this study was to ascertain the flavonoid substance of Apium graveolens and Orthosipon stamineus extracts and their antioxidant activity. The technique comprising qualitative and quantitative phytochemical tests to decide the flavonoid substance of the extracts. In addition, bioactive compounds were screened utilizing LC-HRMS, and antioxidant activity was evaluated utilizing the DPPH technique. The outcomes of this study drawn the presence of flavonoid compounds, alkaloids, tannins, and saponins in the Apium graveolens and Orthosipon stamineus extracts. The Orthosipon stamineus extract was found to contain steroid compounds. The screening of flavonoids compounds utilizing LC-HRMS has drawn the presence of the greatest diversity of flavonoid compounds in the Apium graveolens extract. The antioxidant activity assay employed quercetin as the standard, possessing an IC₅₀ value of 3.95 μg/mL. Apium graveolens extract exhibited an IC₅₀ value of 58.86±0.44μg/mL, Orthosiphon stamineus extract drawn an IC₅₀ value of 61.69±0.21 μg/mL, whereas the combined extract yielded an IC₅₀ value of 46.32±0.34 μg/mL. The outcomes indicate that the extract combination shows superior free radical scavenging ability compared to the individual extracts, suggesting its potential to enhance the antioxidant efficacy of bioactive compounds derived by herbal plants.
Formulation Optimization and In Vitro Antioxidant Evaluation of a Polyherbal Nanosuspension Incorporating Apium graveolens, Centella asiatica, and Orthosiphon stamineus Astuti, Febriana; Akrom; Mustofa; Setianto, Arif Budi; Hidayati, Titiek
Science and Technology Indonesia Vol. 11 No. 1 (2026): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2026.11.1.65-83

Abstract

Antioxidants play a crucial role in protecting cells from damage caused by free radicals, particularly reactive oxygen species (ROS). Herbal plants contain various bioactive compounds, such as phenolics, flavonoids, terpenoids, and alkaloids, which exhibit strong antioxidant properties to neutralize these harmful molecules. However, the bioavailability of these compounds is often limited due to their poor water solubility. Nanotechnology offers a promising solution, specifically through the development of nanosuspensions. This approach enhances the solubility of these compounds by reducing their particle size to the nanometer scale, thus improving absorption in the body. In this study, nanosuspensions were formulated using extracts from Apium graveolens, Centella asiatica, and Orthosiphon stamineus through a two-factor optimization approach with Design-Expert® version 13 software. The optimal formulation contained 25 mL of chitosan, 6 g of Tween 80, and 10 mL of sodium tripolyphosphate (Na-TPP), resulting in nanosuspensions with an average particle size of 220.00(1157) nm, a polydispersity index (PDI) of 0.59±0.06, and a zeta potential of −28.27±0.37mV. The antioxidant activity was evaluated using DPPH and ABTS assays. In the DPPH assay, the nanopolyherbal formulation showed an IC50 of 41.780(3064) μgmL−1, while the combined extract had an IC50 of 44.930(2989) μgmL−1. The ABTS assay revealed an IC50 of 28.21 μgmL−1 for the nanosuspension, significantly lower than the combined extract’s 54.22 μgmL−1. These results highlight the superior antioxidant activity of the nanosuspension, emphasizing the potential of nanotechnology to enhance the efficacy of bioactive compounds from herbal plants.
Ethnopharmacology Analysis of Antidiabetic Medicinal Plants from Menoreh Hills: Linking Local Knowledge to Pharmacological Evidence Kintoko, Kintoko; Faisal Nur Arib; Nanik Sulistyani; Akrom
Journal of Food and Pharmaceutical Sciences Article In Press 2026
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.24603

Abstract

Abstract: The prevalence of type 2 diabetes mellitus (T2DM) has been increasing worldwide and in Indonesia. Documenting locally utilized antidiabetic plants may inform evidence-based phytotherapy. This study mapped antidiabetic medicinal plants in Samigaluh (Menoreh Hills) and prioritized candidates by linking community knowledge with pharmacological data. Semi-structured interviews and observation were conducted between July and August 2025, and involved ten informants selected through purposive and snowball sampling. Quantitative ethnobotanical indices (Use Value, Relative Frequency of Citation, Fidelity Level, Plant Part Value) were calculated, followed by a PubMed-based narrative review. The Zingiberaceae family was predominant (seven species); rhizomes were the most utilized (39.58%), followed by stems (25.00%) and leaves (22.92%). Vernonia amygdalina was prioritized for diabetes-specific consensus (Fidelity Level 100%, Relative Frequency of Citation 0.7), and Curcuma mangga for its high usage and popularity (Use Value 1.3, Relative Frequency of Citation 0.6). Pharmacological evidence indicates that V. amygdalina exhibits antidiabetic effects through the inhibition of α-amylase and α-glucosidase, enhancement of GLUT4, and suppression of gluconeogenesis, supported by its antioxidant and anti-inflammatory properties, while C. mangga demonstrates hypoglycemic activities and β-cell protection, along with anti-inflammatory, antioxidant, and immunostimulant activities as supportive mechanisms. Local knowledge thus aligns with mechanistic findings, supporting a complementary pairing of V. amygdalina and C. mangga for future antidiabetic combinations; further validation through in vitro and in vivo studies is recommended. Keywords: Curcuma mangga; indigenous knowledge; pharmacological evidence; phytotherapy; Vernonia amygdalina
Co-Authors - Sagiran Aa Setiawan Abas, Siti Nur Rahmatiya Abdelghani Echchabi Abdul Aziz Abdul Fadlil Abdul Fat-Han Ismail Abdul Hamid Abdullah Ayedh abdurrahman rahman Ade Permatasari Adeliyanti Adeliyanti Adhy Kurnia Triatmaja Aditya Peramana Maheztra Adnan Adnan, Adnan Adrianison Adrianison Ae Suaesih Afif Alwanuddin Afifah Naziihah Afrizal Afrizal Agamasi, Amalia Agariadne Dwinggo Samala Agesti Hasna Ekawati Agita, Adinda Puspa Agnes Jatiningrum Agung Wibowo Agus Khobir Permana Agus Wibowo Agustina Susilowati Agustyana, Andini Ahmad Bahruddin Ahmad Hafidzul Kahfi Ahmad Naufal, Ahmad Ahmad Suryadi, Ahmad Ahmad Turmudzi Ahmad Turmudzi, Ahmad Ainun Muthoharoh Ainun Rahma Firdausy Ajeng Dianing Kartika Aji, Dicky Qulyubi Akhmad Baihaqi Akmal Hakim Ali Akbar Ali Imron Alif Darmawan Alifah Fidela Allen Pranata Putra Alvenus Willim, Herick Amalia, Farah Amalia, Nur Rizky Amaliyah Tazkiyah Amandha Boy Timor Aminuyati Amir M. Suruwaky Amiruddin Saleh Anak Agung Ayu Sisthayoni Anak Agung Ngurah Yusa Darmadi Ananda, Dhea Andang Adi Fitria Hananto Andi Baso Thabrani Andi Ifriani Harun Andi Ifriani Harun* Andi Pancanugraha Andi Widjaya Andrew John Macnab Andriana Wihartantri Kusumaningrum Andrijono Andrijono Andriyanto Andriyanto Anestia Retno Kusumastuti Anggun Pulihana Wilujeng Anggy Rima Putri Aniq Astofa Anisa Nurfitriana Anita Dwi Putri Galla Annisa Eka Fitrianti Antonius, Rosanio Anwar, Muslih Aprilia Divi Yustita Apriliana Vivy Candra Ardhia Fefrine Indarta Ardianik Ardianik Ardiyanto, Restu Arhandy Arfah Ari Nurweni Ari Pramitha Suandi Ari Simbara Ari Simbara, Ari Arief Rahman Ariestya Indah Permata Sari Arif Budi Setianto Arif Santoso Arifan Q. 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Mangare Jatiningrum, Agnes Jenny Buckworth Joko Dwi Santoso Joko Sudibyo Joko Sudibyo Juhji, Juhji Julita, Julita Kahar, Muhammad Syahrul Kamid, Kamid Karjiyem Karjiyem Karmeliya Firdaus, Mila Karmilasari Keshia Kristin Ketut Adi Riantara Khairul Asri Khairul Saleh Khairul Yadi Khairuni Ismu Khusnul Dwi Istnaini Kinanti, Putri Kintoko Kintoko Koesoemo Ratih Krisna Dewi Kuriasari Pratiwi Kurniawan, Nurcholid Umam Kusdiyanto Kusdiyanto Kusumawardani, Nurul Kyswantoro, Yunita Firdha La Ifa Laela Hayu Nurani Laila Nuranna Laili Apriani Lalu M Irham Lalu Muhammad Irham Lathifah, Sofiani Leni Susanti Lestari Yusuf Lia Nurmalia Lia Riani Liana Mangifera Liesma Yuhelvia Lilis Suryani Lin Suciani Astuti Lina Karlinasari Linda Lestari Loisa Ratna Yuvita Olla Luh Gede Leli Kusuma Dewi Luh Putu Ratna Sundari Lukman Hardia Luky Septiansyah Anjastika M Amar M Arvin Nugroho M. 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