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PESONA HERBAL SEBAGAI UPAYA MENGEMBANGKAN ECO-EDUCATION DAN KEWIRAUSAHAAN PRODUK OLAHAN HERBAL Suryadarma, IGP; Widowati, Asri; Mustofa, Mustofa
INOTEKS: Jurnal Inovasi Ilmu Pengetahuan,Teknologi, dan Seni Vol 17, No 1 (2013)
Publisher : Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (896.509 KB) | DOI: 10.21831/ino.v17i1.3093

Abstract

The activity "The Beauty of Herb" is aimed: (1) to improve the understanding of mother and young man about kinds of herb ans its usefulness; (2) to improve the creativity of mother and young man about way of processing of herb; (3) to improve enterpreneurship of mother and young man. The methods used in trouble-shooting covers: nature exploration, discourse, demonstration and practise. Its steps cover: motivation phase, phase training of theory, and phase training of practise. Data are collected by using quesionare and observasion sheet. Argomulyo's mother and young man respond well by involving actively in every activity phase. This training have earned to improve the understanding of participants about herb ang usefulness. Participant have skill process to process the herbs as products which are prospective They also recognize herbs' product as a business opportunity and intend to plant and propagate herb to others as eco-education.Keywords: The Beauty ofHerb, enterpreneurship, and eco-education
Antiplasmodial activity and cytotoxicity of kapur (Harmsiopanax aculeatus) leaf extracts traditionally used for the treatment of malaria in Maluku Turalely, Rachel; Mustofa; Mahardika Agus Wijayanti; Triana Hertiani
Indonesian Journal of Pharmacology and Therapy Vol 1 No 1 (2020)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.512

Abstract

Harmsiopanax aculeatus leaf, locally name kapur, has been use traditionally to treat malaria in Maluku, Indonesia. However, the scientific evidences that support its use are still limited. This study aimed to investigate antiplasmodial activity of H. aculeatus leaf extract and its cytotoxicity on cancer cells line. Three extracts i.e. methanolic, n-hexanic and ethyl acetate extracts were evaluated for their in vitro activity against Plasmodium falciparum FCR3 strain using microscopic method. Cytotoxicity of the extracts on T47D, HeLa and Vero cells lines were determined using MTT assay method. The inhibitory concentration 50% (IC50) against P. falciparum or the cells lines growth was determined using probit analysis. Furthermore, their selectivity index (SI) were determined. The results showed that the methanolic extract was the most active extract with an IC50value of 13.82 μg/mL and the most selective with a SI value of 172.84. The three extracts tested exhibited weak or no cytotoxicity against the cells lines used with IC50 values ranged 101-2388.69 μg/mL. Further study will be conducted to isolate active antiplasmodial compounds from the methanol extract.
Cytotoxicity of ((E)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one)) on HeLa cell line Adisty Ridha Damasuri; Eti Nurwening Sholikhah; Mustofa
Indonesian Journal of Pharmacology and Therapy Vol 1 No 2 (2020)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.606

Abstract

In our previous study, some amino chalcone derivatives have been synthesized and evaluated their cytotoxicity against breast cancer cell line T47D. Among 11 amino chalcone derivatives, ((E)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one)) exhibited the most active compound.This study aimed to investigate cytotoxic activity of the ((E)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one)) against cervical cell line (HeLa). The cytotoxic activitywas determined using the MTT colorimetric assay. Cisplatin was used as positive control. From this MTT method, inhibitory concentration 50% (IC50) values were determined by probit analysis based on the relationship between log concentrations versus the percentage of cells growth inhibition.The results showed that the IC50 of ((E)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one)) and cisplatinwere 22.75 ± 19.13 μg/mL and 14.96±1.08 μg/mL, respectively. In conclusion, the ((E)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one)) has moderate cytotoxic activity against HeLa cell line based on National Cancer Institute (NCI) criteria.
Synthesis of 3-carbethoxy-4(3’-chloro-4’-hydroxy) phenyl-but-3-en-2-one and its cytotoxicity evaluation against cancer cell carrying mutant p53 Julianus, Jeffry; Mustofa; Jumina
Indonesian Journal of Pharmacology and Therapy Vol 2 No 1 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1211

Abstract

Overexpression of mutant p53 in cancer cell inactivates the p53 pathways to execute apoptosis and cell cycle arrest. This study aimed to synthesize new kardiena derivative compound, 3-carbethoxy-4(3’-chloro-4’-hydroxy)phenyl-but-3-en-2-one, to reactivate the p53 pathways to execute apoptosis and cell cycle arrest. Characterization of the synthetic compound employing melting point, IR, EI-MS, 1H-NMR, and 13C-NMR spectra revealed 3-carbethoxy-4(3’-chloro-4’-hydroxy)phenyl-but-3-en-2-one was successfully synthesized from 3-chloro-4-hydroxybenzaldehyde and ethyl acetoacetate using dimethylamine as a catalyst. This compound had antiproliferative activity against the WiDr cells which carried mutant p53. Its antiproliferative activity was better than 5’-FU as a reference standard to treat colon cancer. Increasing WiDr cell accumulation in the G2-M phase, the active form of caspase-3, and inducing apoptosis demonstrated the ability of 3-carbethoxy-4(3’-chloro-4’-hydroxy)phenyl-but-3-en-2-one to reactivate p53 pathways to execute apoptosis and cell cycle arrest in cancer cells carrying mutant p53.
Antiplasmodial activity and genome mining study of marine-derived Streptomyces sp. GMY01 Damayanti, Ema; Widada, Jaka; Dinoto, Achmad; Mustofa
Indonesian Journal of Pharmacology and Therapy Vol 2 No 2 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1335

Abstract

High resistance to chloroquine in most malaria-endemic area in the world leads to the need for new antimalaria drugs. Marine bacterium Streptomyces is the source for potential new antimalarial molecules. This research aimed to investigate antiplasmodial activity of marine-derived of Streptomyces sp. GMY01 and to identify potential active compounds using genome mining study. In vitro antiplasmodial activity assays using flow cytometry method showed that the ethyl acetate extract of this bacterium had high antiplasmodial activity (IC50 value of 1.183 µg/mL) on Plasmodium falciparum FCR3. Genome mining analysis of whole-genome sequences using antiSMASH 6.0 beta version revealed that Streptomyces sp. GMY01 had 28 biosynthetic gene clusters (BGCs), including the genes encoding polyketide synthase, non-ribosomal peptide synthetase, terpene, lanthipeptide, bacteriocin, butyrolactone, ectoin, siderophore, and others. The known BGCs were predicted to be involved in the production of known compounds from gene clusters ranged from 5 to 100% similarity. Ongoing purification and elucidation of the structures will allow identification of the active compounds produced by marine-derived Streptomyces sp. GMY01.
Antimicrobial activity of Pycnarrhena cauliflora (Miers.) Diels. methanol extract Eti Nurwening Sholikhah; Maulina Diah; Mustofa; Masriani; Susi Iravati; Samekto Wibowo
Indonesian Journal of Pharmacology and Therapy Vol 2 No 2 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1656

Abstract

Pycnarrhena cauliflora (Miers.) Diels., local name sengkubak, is one of indigenous plants from West Kalimantan that has been used as natural flavor. Pycnorrhena cauliflora is one of species of Menispermaceae family which is rich in bisbenzylisoquinoline alkaloids. This alkaloids are known to have various biological activities including antiprotozoal, antiplasmodial, antifungal and antibacterial activities. This study aimed to investigate antimicrobial activity of the P. cauliflora (Miers.) Diels. methanolic extracts against gram-positive and gram-negative bacteria. The methanolic extract of P. cauliflora (Miers.) Diels., root, leaf and stem were prepared by maceration. The disk-diffusion method was then used to determine the antimicrobial activity of the extracts against Streptococcus pyogenes, S. mutants, Staphylococcus aureus, S. epidermidis, Salmonella typhi, Shigella flexneri, Pseudomonas aeruginosa and Escherichia coli after 18-24 h incubation at 37 oC. Amoxicillin was used as positive control for gram-positive bacteria and ciprofloxacin was used as gram-negative bacteria. The inhibition zones were then measured in mm. Analysis were conducted in duplicates. The results showed in general the methanolic extracts of P. cauliflora (Miers.) Diels. root (inhibition zone diameter= 10-23 mm) were more active than that leaf (0-15 mm) and stem (0-17 mm) extracts against gram-positive bacteria. The zone inhibition diameter of amoxicillin as positive control was 8-42 mm. In addition, the methanolic extracts of P. cauliflora (Miers.) Diels. root (12-17 mm) were also more active than that leaf (0-12 mm) and stem (0-12 mm) extracts against gram-negative bacteria. The zone inhibition diameter of ciprofloxacin as positive control was 33-36 mm. In conclusion, the methanolic extract of P. caulifloria (Miers.) Diels. root is the most extract active against both gram-positive and gram-negative bacteria. Further study will be focused to isolate active compounds in the methanolic extract of the root.
The effect of Centella asiatica L. Urban. and Curcuma longa L. extracts combination in improving memory performance in stroke model rats and its acute toxicity Gofir, Abdul; Ar Rochmah, Mawaddah; Wibowo, Samekto; Hakimi, Mohammad; Mustofa
Indonesian Journal of Pharmacology and Therapy Vol 2 No 2 (2021)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.1765

Abstract

Post-stroke cognitive impairment involves memory, visuoconstructional, and spatial dysfunctions. Centella asiatica L. Urban. and Curcuma longa L. are both well-known herbs in South and South-East Asia countries that are believed to possess neuroprotective properties as memory enhancers. This study aimed to investigate the effects of C. asiatica L. Urban. and C. longa L. extracts combination in improving memory performance in stroke model rats and its acute toxicity. Twenty-five Wistar rats underwent transient bilateral common carotid artery occlusion. Y-maze pre-test was performed 24 h after the occlusion. The rats were then divided into five groups i.e. Group 1 received NaCMC dilution, Group 2 received donepezil 0. 7 mg/kg BW/day, and Groups 3, 4, and 5 received the extracts combination with dose of 59; 118; and 236 mg/kg BW/day, respectively. Y-maze post-test was performed 24 h after the last dose had been given. Spontaneous alternation behavior was used as the indicator of working memory measurement. The fixed-dose method according to OECD Guideline was used to estimate the LD50 in acute toxicity testing on Wistar rats. There was a significant difference in the delta spontaneous alternation percentage among groups tested (p<0. 05). Group 1 had significant difference with any other group (compared to Groups 2 to 5; p<0.05). No significant difference could be found between groups of the extracts combination and donepezil group suggesting that the effect is not more inferior nor dose-dependent in improving memory performance. The extracts combination at a single dose of 2000 mg/kg BW did not show related signs of toxicity or mortality in any of the rats during the 14-day observation period. In conclusion, the C. asiatica L. Urban. and C. longa L. extracts combination can improve performance of memory on stroke model animal. According to Globally Harmonized Classification System, the extracts combination can be classified as Category 5/unclassified.
Liposome as carrier therapy for Alzheimer’s disease Anggraeni, Andi Sri Dewi; Arsita, Emilia Vivi; Suwarman, Adika; Mustofa
Indonesian Journal of Pharmacology and Therapy Vol 3 No 2 (2022)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.2315

Abstract

Alzheimer's disease (AD) is the most common type of dementia. Approximately 50 million people suffer from Alzheimer's and it is expected to increase more than 100 million by 2050. According to the Diagnostic and Statistical Manual of Mental Disorders V (DSM-V), the diagnosis of AD has an onset of memory impairment and cognitive decline. Effective treatment of AD is a major challenge in the field of pharmacy and science due to the restriction from blood brain barrier (BBB). This causes poor access to pills or oral administration. Liposome as a part of nanoparticle showed to be a potential AD treatment because of its biocompatibility, flexibility, and capability to carry various therapeutic molecules across the BBB and into brain cells. Several types of liposomes provide varied therapy effect. Some factors which determine liposomes effectiveness are its structure, mechanism of action; formed; and delivery, and its preparation method. This article reviewed liposomes characteristics which has potency as carrier therapy for AD.
Molecular docking study of Indonesian phytochemicals as inhibitor of 6-HB formation by binding to HR1 subunit of SARSCOV-2 S2 protein Julianus, Jeffry; Phebe Hendra; Maywan Hariono; Nico Frederick; Satrio Ardyantoro; Mustofa; Jumina
Indonesian Journal of Pharmacology and Therapy Vol 2 No 3 (2021): Special Issue: COVID-19
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.2392

Abstract

Coronavirus disease 2019 (COVID-19) is still as global pandemic. No officially drugs to treat COVID-19 are available until now. Increasing number of patients and deaths trigger new antiCOVID-19 discovery efforts. In this study, we have conducted in silico screening employing molecular docking for Indonesian phytochemicals. Docking process was performed by employing AutoDock4 software on crystal structure 6VSB. Based on molecular docking results, several compounds had potential as antiCOVID-19 drugs, such as β-carotene, veramiline, ecliptalbine, betulinic acid, and lupeol. β-carotene was the most potential compound to treat COVID-19.
Cytotoxic activity of hantap (Sterculia oblongata Mast) leaves extract against breast cancer cells line (MCF7/HER2): the effect on the expression of HER2 mRNA and the apoptosis Sitti Ayu Suhartina Yahya; Mustofa; Woro Rukmi Pratiwi; Adika Suwarman
Indonesian Journal of Pharmacology and Therapy Vol 3 No 1 (2022)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.3204

Abstract

Hantap leaves (Sterculia oblongata Mast) has been used traditionally to treat breast cancer in Palu, Central Sulawesi. However, its use is just based on empirical evidences rather than scientific evidences. The study aimed to investigate the cytotoxic activity of hantap leaves extracts against breast cancer cells line. The effect of this extract on the HER2 expression and the apoptosis was also evaluated. The hantap (S. oblongata Mast) leaves extracts were prepared by consecutive maceration method using n-hexane, methanol and water, respectively. The cytotoxic activity against MCF7/HER2 breast cancer cells line was evaluated using the MTT assay with doxorubicin as a positive control. The HER2 mRNA expression was examined using RT-PCR and the apoptosis after 24 h incubation was examined using a fluorescence microscope after AO-PI (acridine orange-propidium iodide) staining. Among three extracts tested, the methanolic extract exhibited the most cytotoxic against MCF7/HER2 cells with an IC50 of 91.25 μg/mL. Therefore, the methanolic extract was subjected to further study. The methanolic extract at concentration of 1/2IC50; 1IC50 and 2IC50 μM induced 6.8; 26.3 and 25.3% apoptosis of the MFC7/HER2 cell lines, respectively. The methanolic extract at concentration of 1/2IC50; 1IC50 and 2IC50 μM inhibited HER2 mRNA expression to be 0.6; 0.25 and 0.33 compared to control cells. In conclusion, the methanolic extract of hantap leaves (S. oblongata Mast) has cytotoxic activity against MCF7/HER2 breast cancer cell lines by induce cells apoptosis and inhibit HER2 mRNA expression. Further study, will be conducted to isolate active constituents as anticancer.
Co-Authors -, Nasiri A Halim A. Fitriani Abas, Rizan Abdilah, Ulil Absor Faiq Abdul Gofir Abdul Hakim, Al Hasan Abdul Kholik Abdul Manaf Ali, Abdul Manaf Abdul Rahim Abdul Rokhim Abdul Wahid Abdullah, Rizky Achmad Dinoto Achmad Sehan Ade Nur Rohim Ade Setiawan Adi Putranto, Hanafi Adika Suwarman Adisty Ridha Damasuri Aditama, Wahyu Aditia Dhani Mustofa Afib Rulyansah Agus Faisal Asyha Agus Luthfi Agus Pahrudin agus prasetyo aji Agus Sugiarto Agus Supriadi Agussalim Agustin HP, Agustin Agustina, Feny Rizki Eka Ahmad Asrof Fitri Ahmad Hamim Sadewa Ahmad Khoirul Fata Ahmad Nouvel - AMIK BSI Purwokerto Ahmad Nouvel - AMIK BSI Purwokerto Ahmad Sauqi Ahmad Syaifuddin Romli Aini, Saqofa Nabilah Akhmad Akbar Susamto Akhwani Akhwani Akhwani, Akhwani Akrom, Akrom Akuba, Syamsu Al Hakim, Mahathir Muhammad Alatas, Haidar Alexis Valentin, Alexis Alfi Yasmina Alfinatus Zayyinah Alfiyah, Viny Alfiyantani Nugroho Ali Djamhuri Ali Ghufron Mukti Ali Muhson alimin alimin aliyah, faridatul Aliyah, Roudlotul Almurni, Muhammad Furqon Amri, Aini Nurul Anani, Siske Andayani, Tri M. Andi Hairil Alimuddin Andi Namirah Muh. Syuaib AS, Andi Andini Hardiningrum Andrian Saputra Ange Desire Yapi, Ange Desire Angga Ade, Permana Angger Styo Yuniarti Anggraeni, Andi Sri Dewi Ani Widayati Ansori, Mukhamad Yusuf Anwar, Muslih Apriani, Hikma ARDIANSYAH, JEFRI Arfiani Nur Arief Agoestanto Arief Budiyanto Arif Budi Setianto Arif Budiman Arina Selawati Arini Arini Aristia, Bella Fevi ariyanti, firda aulia Arum Darmawati Arviyah, Vira Aryati, Ani Asep Kurniawan Asri Widowati Astuti, Rachma Darma Astuti, Rachmawati Darma Atikah, Ika Audita Nuvriasari Aufa, Mohammad Zidan Aula Ahmad Hafidh Saiful Fikri Awal Syahrani Sirajuddin Ayesa Zahwa Amelia AYU WULANDARI Azizah, Nuryana Elia B. Handoko Purwojatmiko Badrudin Baehaqi Baijuri Bambang Suhartono Baso Intang Sappaile, Baso Intang Basri Basri Bawazier, Lucky Aziza Bayu Prio Septiantoro Bayu Supriyadi Bonartua Hutapea, Edison Brilian, Dion Nicky Buchori, Muhamad Budi Sasomo, Budi Budi Tresnayadi Catur Sugiyanto Chairil Anwar Chintyasari, Shaula Curatman, Aang Dadi Mahardi Dafitri, Rizkika Daniel Parenden, Daniel Danny Syamsu W Danto Danto, Danto Daru Wahyuni Dede Nurwahidah Dedy Wijaya Kusuma Desi Suci Handayani Dessy Susanti, Inggit Destita Shari Dewi Sadiah, Dewi Dewi Sulistiyarini Dewi, Wulan Rahma Dhina Fitriastuti Diana Diana Diana Dwi Astuti Djoko Wahyono Donant Alananto Iskandar, Donant Alananto Dwi Ferdiyatmoko Cahya Kumoro Dwi Puryanti Dwi Siswanta Dwi Widiastuti, Dwi Dyah Aryani Perwitasari Edy Turjono Eka Ary Wibawa Eko Budiono Ema Damayanti Emilia Vivi Arsita Emmy Hamidah Emmy Hamidah Encep Taufik Rahman Endah Puji Septisetyani, Endah Puji Endang Darmawan Ending Solehudin Eriek Aristya Pradana Putra Erna Kristin Eti Nurwening Sholikhah Eva Rahmawati Evi Mulyani Evi Sunarti Antu Fabriyan Fandi Dwi Imaniawan Fadhilah, Putry Fahrezi, Fajar Fahrur Razi Faisal, Agus Faiz, Afiyatul Mahfudloh Faqih, Muhammad Izzatul Faruq, Muhamad Fathur Rozi Fatmawati, Risdiana Andika Fatun, Fatun Fauzi, Ghizela Fineartha Fazila, Nisa Febriana Astuti Febriansah , Rifki Febriyanto, Mohammad Fernanda Al Welery Fezzi Reri Fikri, Aula Ahmad Hafid Saiful Fitranto Arjadi Fredie Irijanto Gigih Hilmiawan Gilang Pratama Gumel, Salisu Gumel, Salisu Muhammad Gunawan Gunawan Gunawan Gusti Nyoman Budiadnyana Hadi, Aminulloh Hadi, Ismanurrahman Hafizah, Noor Haifah, Haifah Haitham Hanifah Yusuf Haqiqi, Adif Farhian Harahap, Arifuddin Muda Hariadi Hariadi Harini, Ika Murti Hariyadi, Ari HARIYANTO HARIYANTO Haryadi Hasan, Zainol Hastadi, Andre Yasip Hayatul Maspufah Heny Ekawati Haryono Heriyanto Heriyanto Herman Cahyo Diartho Heru Agus Cahyanto, Heru Agus Heru Purwanto Hidayat, Agi Attaubah Hidetaka Kawakita Hisam Ahyani Holil Houtman Huddin, Misba I Dewa Putu Pramantara Setiabudi I Nurol Aen Idris, Irma Surya Kumala Idris, M. Manshur IGP Suryadarma Iim Wasliman Iis Nur Asyiah Ika Puspita Sari Ilmiyah, Izzatul Imam Haryono Imam Sujono Inayati Inayati Indah Purwantini Indah Rahmawati Indra Utama Tanjung Indwiani Astuti Iqmal Tahir Irawan Irawan Irfansyah, Putra Irsyansyah, Irsyansyah Isa, Abdullah Iskandar Iskandar Iskandar Ritonga Isma, Khilyatul Isnaini Maulidatu Nisa Istajib Kulla Himmy Azz Istiqomah, Titis Iswavigra, Dwi Utari izza, Aqidatul Jaenuddin, Jaenuddin Jaka Suwita JAKA WIDADA Jamaludin, Jujun Jastria Pusmarani Jauharotur Rihlah Jayawarsa, A.A. Ketut Jeffry Julianus Jefry Tarantang Jemain, Zulkipli Jenny Hidayat Jordy Lasmana Putra Jubaedah, Dedah Jumina Jumina Kartono, Munir Kasduni Keisuke Ohto Kennedy, Kennedy Khasanah, Uswatul Khoirul Fata, Khoirul Khoirun Nisa Khotib Khotib Khotib, Khotib Khusniyah, Siti Alfitrotul Kistiananingsih, Isti Kristian Selleng Kuncoro, Prasetyo Tri Kurani Mega Asteroid Kurnaesih, Uun Kurnia, Heri Kurniawati, Resty Amelia Kushariyadi Kushariyadi Kusuma, Nurul Rahmah Kusumasari, Dyah Kusumawati, Nyimas Inda Latif, Lita Asyriati Leo Soemardji Lilia Pasca Riani Listini Listini, Listini Lorettha Wijaya Losina Purnastuti Luluk Faridah Lutfiyani, Intan Qori M Rusdi M, Nurdiana M. Satrio Setia Budi Ma'ruf, Attabik Hasan Madani, Arya Indra Mafrudlo, Ahmad Mahfudzi Maftuh, Abdullah Maghfiroh, Annisatul Mahardika Agus Wijayanti Mahardika Agus Wijayanti Mahmudah, Himmatunnisak Maimun Sholeh Makki, Hali Malasari, Putri Nur Mansur, Zuhratul Aini Marhadi Saputro Mariani, Scholastika Marlinda, Dwi Marstyawan Marstyawan Mar’atullatifah, Yulaikha Maslachah, Cholilatul Masriani . Masrid Pikoli Maulina Diah Mawaddah Ar-Rochmah Maywan Hariono Medi, Gery Meirina Suci Ridha Melia, Anissa Dwi Melia, Annisa Dwi Meti Fatimah Mintarsih, Betty Mintarsih, Betty Misba Huddin Mislan Moh. As’ad Mohamad, Roni Mohammad Hakimi Muadib, Ihwanul Mubarika Mubarika Muchsin Muchsin Muflikhah, Khusnul Mufrida, Farah Fergi Muhammad Dala Rizfie Muhammad Fajar Muhammad Idham Darussalam Mardjan Muhammad Nur, Hidayat Muhammad Nurkholis Kholik Muhammad Yazid Muharir, Muharir Muharromah, Gabriele Lailatul Mukammilah, Mukammilah Mukhlas, Oyo Sunaryo Mulyadi Mulyadi Mulyani Surendra Mulyono Mulyono Mumtaza, Alif Nafiatul Mun'im, Muhammad Hasan Munawar, Agus Muqoddaroh, Fadillatul Mursalim Mursalim mursid, fadillah Musaiyadi Musaiyadi Musawir, Musawir Musriatun Napiah Musri’ah, Musri’ah Mustofa, Ismail Muthi Ikawati Mutmainah, Naeli Muvita Rina Wati Nafi'ah, Nafi'ah Nahadia, Risna NAJIB, GILMAN AIMAN Nasiruddin, Atsir Faris Nasrudin Natasyah Asviana Naufal, Ahmad Maulidin Nazudin, Nazudin Nenden Susilowati NETTI KARIANI MENDOFA Ngadiyono Ngadiyono, Ngadiyono Nico Frederick Nisa, Shinta Khoirun Nisak, Sayida Khoiratun Nita Kusumawardani Nita Suleman Nofia Sari, Okta Noval Cahyo Triyanto Noventi, Iis Novita Carolia Nugraha, Raffy Ave Nur Azizah Nur Fadillah, Nur Nur Rochmat Nur Sakinah Nur Signa Aini Gumilas Nuraini El Fajri Nurfaizah, Ani Nurhayati Nurhayati Nurhayati, Is Nuriman Nuriman, Agus Nurkolis Nurkolis, Nurkolis Nurmaulida, Regita Okti Nurrohman Nurrohman Nursari, Nina Nursyahira, Kasandra NURUL FAIZAH Nurul Hidayah Almubarokah Nuryani Nuryani Oktaviyah, Dayanti Paisal, M. Pakaya, Renaldi Pamudji, Rama Adistya Nurcahya Pamuraharjo, Hemi Pangestu, Herwindu Danu Parwanti, Sri Pasai, Muda Wali Samudra Pekerti UA, Pekerti Permatasari, Armita Pertiwi, Rini Wahyuning Phebe Hendra Piarah, Wahyu Haryadi Podungge, Djamila Prabowo, Arif Agung Pranidya, Cici Dwi Praseno Praseno Prasetya, Dimas Prasetyo, Deny Prastiyo, Rian Pratama, Dinar Rezky Prihatin Oktivasari Probosuseno Probosuseno, Probosuseno Purwandari, Elce Purwanti, Nunik Puspa, Eka Septariana Puspasari, Novela Putri Puspitaningrum, Yuliastuti Putra, Haris Maiza Putra, Ihrom Caesar Ananta Putri, Depi Putri, Nadia Tiara Putri, Vanesa Adelia Qodariyah, Niyar Ana R, Agam Bahtiar Rabbani, Davis Ovisena Rachel Turalely Raharjo, Mugi Rahayu, Dewi Widiana Rahim, Abd Rahmadanti, Putri Rahmah, Suqya Rahmani, Mawardi Rahmani, Mawardi Rahmat Dani Rahmatulloh, Asep Rahmawati, Indriyani Dwi Rahmawati, Lilik Ratna Asmah Susidarti Ratna Asmah Susidarti Ratna Dewi Kusumaningtyas Refson Refson, Refson Reni Nurjasmi, Reni Retikasari, Frysca Virnanda Retno Murwanti Retno Wahyuningrum Rian Byhaqi Rias Gesang Kinanti Ridwan, Ahmad Hasan Ridwan, Vicky Bahru Rifky, Rifky Riyansyah Rizfie, Muhammad Dala Rofiq Sunaryanto Rohimah, Titi Rohma, Adelia Nur Rohmah, Ainun Roni Mohammad Rosita, Chintya Royhan, Royhan Rukmana, Andi Rulyansyah, Afib Ruslin Hadanu Rusmana, Najwa Rokhan Rustan Hatib S Mursiti S Siswanto Sabirin Matsjeh Saepul Nugraha Safarudin, Muhamad Sigid Safitri, Anggi Safitri, Erica Meilia Said, Andika Pratama Said, Moch Imron Salim, Helmi Agus Salsabila Imarotul Maftuhah Salsabila, Anisah Fithriyyah Samekto Wibowo Samekto Wibowo Santi Rosniawaty Saptono Saputri, Adinda Rizky Eka Saputri, Ginandjar Zukhruf Sari, Elisa Mardita Sari, Nurita Sari, Rosyidah Hikmah Sariman, Farid sarwo edy Satria Wati Pade Satrio Ardyantoro Sejati, Hiro Selirowangi, Nisaul Barokati Seto, Bayu Setyawan A, Setyawan Setyo Rini, Asih Shalsabila Azzahra Sherin Ramadhania Shinta Ayu Lestari Shodiq, Achmad Shofwatun Hasna Shukatin, Shukatin Sidiq, Sidiq Sinensis, Rizki Amelia Sinrungtam, Wasana Sinta Suleman Siradjuddin Haluti, Siradjuddin Sirotjuddin, M. Siti Aimah Siti Hamidah Siti Maghfirotun Amin Siti Maimunah Siti Musyrifah, Siti Siti Rahimah Siti Rodhiyah, Siti Siti Romlah Sitti Ayu Suhartina Yahya Sja'bani, Mochammad Soedjono Aswin Soedrijanto, Angky Sofiana, Elda Sofiana, Nabila Okta Sonny Taufan Sri Handayani Sri Hartatik Sri Haryanti Sri Juari Santosa SRI RAHAYU Staddal, Iqrima Subaidi Subyanto, Subyanto Suharyanto H. Soro Suherli, Ian Rakhmawan Sukanta, Deris Samba Pordi Sukari, Mohd. Aspollah Sukari, Mohd. Aspollah Sukidjo . Sulaeman Sumarta Sumbodo, Mugiatno Sun, Suny Sunanto Sunanto Sunarti Sunarti Sunaryati Supendi, Dede Supriatini Supriatini Supriatini, Supriatini Supriyanto Supriyanto Supriyanto SURADI, A Suradi, Amran Surismiati Surismiati Suriyana Suriyana Suryani Suryani Susanti , Yuli Susi Iravati Susiana Candrawati Susy Yunita Prabawati Sutirman Sutirman Suwarman, Adika Suyahman Suyahman Suyanto Suyanto Syamsul Ghufron Syarief, Ali TAUFIK ROHMAN, TAUFIK Thina Oktarina Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tonny Ari Wibowo Tresna Dewi Tri Cahayati, Ulinnuha Tri Lestari Triana Hertiani Triana Kusumaningsih Tryono, Agus Tsaabitah Jihaan Sabrina Tsumu, Dhatu A Udi, Moh. Usni Putri, Saifa Utami, Satiti Vadlya, Vadlya Maarif Vero Ferdinand Putra Suseno VIKTARIA, Venansi Wachda, Mazayatun Nissa’ul Wahyono Wahyono Wahyuni, Ane Tika Wahyuni, Fina Tri Wahyuningsih, Fetri Warang, Japri Yusrifal Wardani, NIta Kusuma Wasliman, Eva Dianawati Whan Augustin Ainul Amri Wibowo, Prasetyo Agus Wicaksono, Ardy Wicaksono, Nicky Gilang Widya Asmara Wijaya, Rahman Benta Wina Libyawati, Wina Wisesa, Sindhu Wiwiek Fatchurohmah, Wiwiek Wiwik Cahyaningrum Woro Rukmi Pratiwi Wulan Rahma Dewi Wulandari, Friska Tri Wulansari, Rahmawati Wuni Sapoan, A’is Mulie Yadi Janwari Yamin , Muhammad Yanti Dwi Astuti, Yanti Dwi Yanuar, Rahmat Yasri Rahmawati Yayi Suryo Prabandari Yayuk Dwi Rahayu, Yayuk Dwi Yoga Prihastomo Yoga Prihastomo Yohandri Bow Yudithia Maxiselly Yuli Asmi Rahman Yuliansah Yuliansah Yumna, Isna Aulia Yunianto Agung Nugroho Yuniarti, Angger Styo Yusman, Nurjannah Zahroh, Faiqotus Zainuddin, Faiz Zainuri Zainuri, Zainuri Zakiyah, Makhshushi Zikri Marifatullah Zuhratul Aini Mansur Zulaela Zulaela, Zulaela Zulkaisni, Zulkaisni Zuryati Djafar